Mission Bio Tapestri® Platform
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Mission Bio Tapestri® Platform - 1

Tapestri Platform for Single-cell Multi-omics Uncover genotype and phenotype insights simultaneously from single cells Status: Running

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Mission Bio Tapestri® Platform - 2

Unravel cancer's complexity with true single-cell multi-omics The Tapestri® Platform is the world's first and only single-cell solution that provides both genotype and phenotype data from the same cell. Based on a novel two-step microfluidic workflow, the Tapestri Platform can access DNA and protein in single cells to give you a true multi-omics picture. With its unprecedented speed and scale, you can now get actionable insights needed to get to the ground truth and unravel the threads of cancer's complexity. Tapestri Platform Highlights Analyze DNA and protein expression simultaneously in...

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Mission Bio Tapestri® Platform - 3

The importance of understanding cancer at a single-cell level Cancer is a heterogeneous disease. In order to resolve heterogeneity and improve patient stratification, therapy selection, and disease monitoring, you need a tool that provides a holistic view of a cell, integrating data across multiple dimensions. Unlike bulk sequencing, single-cell multi-omics enables you to: • Detect rare cell populations • Measure zygosity • Identify co-occurring mutations • Resolve clonal heterogeneity CLONAL RESOLUTION WITH SINGLE-CELL PRECISION In order to see the evolution you need to understand the...

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Mission Bio Tapestri® Platform - 4

Tapestri Single-cell DNA panels allow you to focus on the mutations and regions of interest that are most relevant to your disease research. Select from pre-designed panels carefully curated for a range of cancer research areas to get your lab up and running with minimal time and effort. Alternatively create a fully customizable panel for utmost flexibility. Oligo-tagged protein antibodies can be integrated to your Tapestri experiments to enable concurrent measurement of proteins, uncovering both genotypes and phenotypes from the same cell. Applications include hematological malignancy,...

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Mission Bio Tapestri® Platform - 5

End-to-end solution that seamlessly plugs into your NGS workflow Use the Tapestri instrument, reagents and consumables up-front of your NGS system and then Tapestri Pipeline and Taprestri Insights software for data analysis and visualization. THE TAPESTRI WORKFLOW The Tapestri Workflow TARGET SELECTION SAMPLE PREP LIBRARY PREP CHOOSE A PREDESIGNED OR CUSTOM DNA PANEL ADD A PROTEIN PANEL AND SIMPLE CELL STAINING PROTOCOL SINGLE WORKFLOW COMBINES DNA AND PROTEIN PANELS SINGLE SEQUENCING RUN FOR MULTI-OMICS SINGLE-CELL DATA INTEGRATED PIPELINE FOR MULTI-OMICS ANALYSIS POWERFUL ANALYSIS AND...

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Mission Bio Tapestri® Platform - 6

CONTACT US Mission Bio, Inc. 6000 Shoreline Court, Suite 104 South San Francisco, CA 94080 + 1.415.854.0058 info@missionbio.com www.missionbio.com For Research Use Only. Not for use in diagnostic procedures. © 2020 Mission Bio, Inc. All rights reserved. Brochure_MissionBio_Tapestri_Platform_RevF

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