Multiwell-MEA-System

Product catalog summary

Overview
The Multiwell-MEA-System is a high throughput electrophysiology system designed for use with 24- and 96-well plates, featuring up to 1152 electrodes. It supports a high sampling rate of up to 50 kHz per channel and includes integrated stimulators and various well plate variants to accommodate different experimental needs.

Technical Specifications

General Characteristics: The headstage measures 302 mm x 166 mm x 90 mm and weighs 4 kg, while the interface board is 250 mm x 83 mm x 25 mm, weighing 0.3 kg.
Amplifier: Provides 24-bit data resolution with 288 recording channels and a bandwidth of 0.1 Hz to 10 kHz.
Stimulus Generator: Capable of current stimulation of ±500 µA and voltage stimulation of ±10 V.
Data Converter and USB Interface: Utilizes USB 3.0 with a sampling rate of up to 50 kHz per channel.
Heating Element and Temperature Sensor: Equipped with a PT 100 sensor with an accuracy of ±0.1 °C.

Software
The system operates on Windows 8.1 (64-bit) and supports data acquisition through Multiwell-Screen software (version 1.5.6.0 and higher) and analysis via Multiwell-Analyzer (version 1.2.3.0 and higher). The software facilitates real-time data display, filtering, and automatic dose-response curve calculation.

Well Plate Variants
Available in different types, including glass and epoxy bases, with varying electrode diameters and interelectrode distances. Each variant includes reference electrodes for precise measurements.

System Components
The system consists of four main components: the headstage, interface board, PC & software, and well plates. The headstage is essential for signal amplification and digitization, while the interface board ensures data synchronization and connection to a computer.

Key Features

Automated report generation and flexible data export options.
CiPA compliant plate layout templates.
Support for single and cumulative dosing.
Integrated temperature control and climate chamber for noise-free recordings.

Conclusion
The Multiwell-MEA-System is a versatile tool for electrophysiology, offering high-resolution data acquisition and analysis capabilities, suitable for both neuronal and cardiac cell studies.

Catalog excerpts

Multiwell-MEA-System: Technical specifications General characteristics Dimensions (W x D x H) Weight Headstage: 4 kg Interface board: 0.3 kg Amplifier Data resolution Number of recording channels Stimulus generator Current stimulation Voltage stimulation Data converter and USB interface Control interface Sampling rate per channel Heating element and temperature sensor Temperature sensor type PT 100 with 4 wire connection Software Operating system Data acquisition Multiwell-Screen, Version 1.5.6.0 and higher Analysis software Windows 8.1 (64 bit) (English and German versions supported) Multiwell-Analyzer, Version 1.2.3.0 and higher High throughput electrophysiology Well plate variants Type of well plate Base material Glass Epoxy Epoxy Epoxy Glass Interelectrode distance (center to center) 300 µm 700 µm 700 µm 400 µm 700 µm Electrodes per well 12 + 4 reference 12 + 1 reference 3 + 1 reference 12 + 2 references 3 + 1 reference • 24- and 96-well plates with up to 1152 electrodes visit: physiology r electro olutions fo te s For comple hys.com .smart-ep www • Up to 50 kHz sampling rate • Integrated stimulator Multi Channel Systems MCS GmbH © November 2018 Multi Channel Systems MCS GmbH Product information is subject to change without notice. Products that are referred to in this document may be either trademarks and/or registered trademarks of the respective owners. The publisher and the author make no claim to these trademarks. • Different well plate variants Aspenhaustrasse 21 72770 Reutlingen Germany

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High throughput electrophysiology for screening Multiwell headstage Data analysis with Multiwell-Screen software Featuring a 24- and 96-well plate format, the Multiwell-MEA-System from Multi Channel The headstage is the core element of the system. It houses the well Systems is the perfect tool for medium and high throughput electrophysiology. Being plate, amplifies and digitizes the signals, and has an integrated stimulus based on the MEA2100-technology, it includes high-quality, low-noise amplifiers, freely- programmable stimulators, and a digital signal processor for individual analyses. The...

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