multichannel1? systems a division of Harvard Bioscience, Inc. Data Acquisition and Analysis Software • In vivo Electrophysiology • In vitro Electrophysiology • Microelectrode Arrays • Patch Clamp • Xenopus Oocyte Research • Stimulus Generators • Electrophysiological Laboratory Equipment

SmartE p hy S ◦ Harvard Bioscience, Inc. brand multichannel^ systems WARNER INSTRUMENTS www.smart-ephys.comFour trusted brands working together for you Combining our expertise and experience, we now offer complete solutions for all areas of electrophysiology under the umbrella of "Smart Ephys". You will still find the high-quality products and unmatched support you are used to from HEKA, Multi Channel Systems, Triangle BioSystems International, and Warner Instruments, but now all from one source. We look forward to continuing as a trusted partner in your laboratory, finding the right solution...

Contents Software • Data acquisition and analysis Page 2 In vivo Electrophysiology • Amplifying, recording, analyzing, and stimulating Page 8 In vitro Electrophysiology • Amplifying, recording, analyzing, and stimulating Page 12 Microelectrode Arrays • Contacting Page 18 Patch Clamp • Automation of classical patch clamp Page 24 Xenopus Oocyte Research • Automated injection • Automated electrophysiology Page 26 Stimulus Generators • Current and voltage driven stimulation Page 30 Electrophysiological Laboratory Equipment • Complete solutions for electrophysiology Page 32 Beyond the physical product...

Software • Data acquisition and analysis Flexible and powerful: Multi Channel Suite • Data acquisition and analysis Medium and high throughput screening experiments: Multiwell-Screen and Multiwell-Analyzer • Data acquisition and analysis Network analysis by electrical imaging: CMOS-MEA-Control and CMOS-MEA-Tools • Data acquisition and analysis Excitation patterns, conduction velocity studies, and QT-prolongation studies: Cardio2D • Data acquisition and analysis Long-term potentiation and depression studies: LTP-Directo

Flexible and powerful Application Multi Channel Suite is a complete software solution for reliable acquisition and analysis of electrophysiological data. Real-time recording, graphing, and analysis of extracellular activity of excitable cells for in vivo and in vitro applications. Multi Channel Suite Data acquisition and analysis Product Features Introduction • Consists of three tools: • Experimenter for recording and online analysis • Analyzer for offline analysis • DataManager for exporting to other programs (Python, Matlab, Neuroexplorer etc) • Free software updates from our website • Free...

Medium and high throughput screening experiments Application The Multiwell-Screen software package is designed specifically for the needs of screening experiments with the Multiwell-MEA-System. It is the ideal solution for drug screening and discovery as well as safety pharmacology. In the beginning, you select whether you record from neuronal or cardiac cells, and then have a tool set specialized for your application. Multiwell-Screen Data acquisition and analysis Introduction With both tool sets, you can display your data in realtime on the entire well plate, zoom into one single well and see...

Network analysis by electrical imaging Application The CMOS-MEA-Control/CMOS-MEA-Tools software package is designed for the analysis of spontaneous or evoked spikes and LFPs in tissue preparations or cell culture with unparalleled temporal and spatial resolution. Data acquisition and analysis Product Features • User friendly • Adaptive filtering • Flexible recording control • Stimulation with highest spatial resolution • On-line spike detection and streaming • Activity summary generation • Spike triggered average movies Introduction Data acquisition with the CMOS-MEA5000-System...

Excitation patterns and conduction velocity studies Application Cardio2D is used to acquire and analyze field potential data from cardiac cells, tissue and whole organs via microelectrode arrays (MEA) and flexible MEAs. The software has a mapping module for the analysis and visualization of cardiac signal propagation patterns and the measurement of conduction velocity. There is also a module that allows analysis of the field potential duration - a surrogate marker for the action potential duration and QT-Interval in the ECG. Product Features Cardio2D has a data acquisition and an analysis module....

Long-term potentiation and depression studies LTP-Director Application LTP-Director is a specialized software solution to run standardized LTP (long-term potentiation) experiments in hippocampal slices. It features complete control of recording and stimulation, as well as automated perfusion, online data analysis, and documentation of the experiments. Product Features Data acquisition and analysisIntroduction • User friendly • Standardized experiments • Control stimulation • Control drug delivery and perfusion • Automated report sheet generation Technical Data Operating system The LTP-Director/LTP-Analyzer...

In vivo Electrophysiology • Amplifying, recording, analyzing, and stimulating Wireless in vivo System • Amplifying, recording, and analyzing Portable-ME-System • Amplifying, recording, analyzing, and stimulating Tethered ME2100-System

W2100-System Product Features 4, 8, 16 or 32 channels Lightweight headstages Wide effective range (5 m) Excellent signal-to-noise ratio Options for electrical and optical stimulation Headstage Types multichannel*? systems Application Recording and stimulation of neuronal activity in freely moving animals. Amplifying, recording, analyzing, and stimulating Option to access analog data Parallel recordings possible Synchronized video-to-data recording possible Introduction The W2100-System is the all-in-one solution for amplifying, recording, and analyzing in vivo data from up to 32 channels. The...