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MODEL TMW-4012C (10kW)

MODEL TMW-4012C (10kW)

MODEL TMW-4012C (10kW)

Product catalog summary
Introduction
In neurochemical studies, accurately measuring neurochemical events in vivo is crucial. Traditional methods like cooling or freezing are not fully effective due to the poor thermal conductivity of brain tissues, leading to post-mortem changes. The Muromachi Microwave Fixation System offers an alternative by using microwave heating to rapidly inactivate enzymes, allowing for accurate measurement of various neurochemicals such as Acetylcholine, Choline, and others.

System Requirements
The system must elevate brain temperature to 75-90ºC quickly, focus microwave energy on the animal's head, provide consistent results, and be user-friendly and safe, with microwave leakage not exceeding 5 mW/cm2.

Specifications
  • Oscillator: Toshiba Magnetron 2M68(A)
  • Microwave Power Output: 10 kW max.
  • Oscillation Frequency: 2.450±30 MHz
  • Cooling Requirements: Water Cooling, 3 liters/min
  • Exposure Time: 0.01 - 2.99 sec (0.01 sec steps)
  • Pausing Time: 3 min
  • Power Consumption: 19 kVA
  • Frequency: 50 or 60 Hz
  • Power Requirements: 200/220V AC 60A 3Phase
  • Dimensions: W935 x D640 x H1,310 mm
  • Weight: Approx. 240 kg

Applicator Head and Animal Holders
Various applicator heads and animal holders are available for different sizes of mice and rats, ensuring proper fit and effective microwave application.

Standard System Components
  • Main Unit (TMW-4012C)
  • Applicator Head (one from the list)
  • Animal Holder (one from the list)
  • Dust Cover

Specifications are subject to change without notice.
See more

Catalog excerpts

MODEL TMW-4012C (10kW)-1

Prior to analyses of •Acetylcholine ® Choline ® Cyclic AMP • Cyclic GMP • GABA • DOPA • 5-HTP • Serotonin • Endorphin ® Catecholamines and their metabolites ® Prostaglandin • Phosphorylated Proteins • Glycogen

 Open the catalog to page 1
MODEL TMW-4012C (10kW)-2

INTRODUCTION In neurochemical studies of the brain, it is of great importance to accurately measure neurochemical events in vivo. However, it is difficult to perform reproducible and meaningful measurement of these events because rapid post-mortem changes occur in the brain concentrations of several metabolites and some neurotransmitters. Therefore, various techniques have been developed to prevent post-mortem changes. One of the more common method is cooling or freezing by immersion of the living animal and the decapitated head in liquid Nitrogen or cooled Freon to inactivate enzymes involved...

 Open the catalog to page 2
MODEL TMW-4012C (10kW)-3

Effect of microwave irradiation on Fiir.2 Effect of microwave irradiation on Figr.3 Effect of microwave irradiation on and ChE activities in rat brain. T-OH and MAO activities in rat brain. GAD and GABA-T-SSADH activities in rut MICROWAVE EXPOSURE(sec Effect of microwave irradiation on Lilect of microwave irradiation on AC and cAMP-PDE activities in rat brain. GC and cGMP-PDE activities in rat brain. Male Wistar rats weighing 150 were exposed to microwave irradiation at a power level of 5hv\ for the period After the irradiation whole brain mm us cerebellum was homogenized and subjected to...

 Open the catalog to page 3
MODEL TMW-4012C (10kW)-4

APPLICATOR HEAD Mouse Holder) Water-Jacketed Animal Holders Specifications are subject to change without notice. MUROMACHI KIKAI CO., LTD. 4-2-1 Nihonbashi-Muromachi, Chuo-ku, Tokyo, 103-0022 JAPAN TEL+81-3-3241-2444

 Open the catalog to page 4

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.