CardioExcyte 96
6Pages

Contractility. Electrophysiology. Viability.

CardioExcyte 96 Label-free cardiac safety screening • 96 recording wells in parallel • Real-time access to beating parameters • Contractility, viability & electrophysiology • Incubation System • Non-invasive & label-free measurements • Cost efficient consumables • Monitoring acute and chronic effects • Transparent plates for imaging available • Electrical and optical pacing options • Ideal for cardio-oncology and cyto-tox • Integrated liquid handling system • utstanding data analysis software O short term effects Cardiotoxicity screening on beating cellular network The CardioExcyte 96 is a...

CardioExcyte 96 Specifications: supported recording modes: impedance /EFP resolution & bandwidth: Impedance spectral range: temperature sensing: 0.1-100 kHz multi-sensor temperature control validated induced human pluripotent stem cells: Cor.4U®, iCell®, Cellartis hiPS-CMTM, ReproCardioTM 2, Pluricyte validated human embryonic stems cells: hES-CMCTM, CytivaTM impedance-, electric field potential (MEA-like) recordings Imp: 1-10 ms, 0-500 Hz / EFP: 0.1-1ms, 0.1Hz-5kHz parallel recording channels: 96 stand-alone system: automated liquid handling: integrated Incubation System Integra Viaflow...

DataControl 96 Software Package. Versatile data analysis & data handling. The CardioExcyte 96 control software supports online analysis of beating parameters. The unique Mean Beat Function automatically visualizes the average of beat traces from one well, enveloped by the standard deviation, indicating the consistency of the beat pattern within the recording well, i.e. if the cellular network is synchronously beating or not. The control software is intuitive and easy-to-use, at the same time very powerful in terms of experimental set-up and online visualization of the recorded data. The...

96-well live view showing dynamic impedance and impedance baseline. Mean Beat Function explained Averaged trace: Single-well detailed view allowing zoom in and trace selection, here showing mean beat signals. Red traces show the standard deviation from the mean. 16-well group view: mean beat traces (and SD in red) from selected wells. CardioExcyte 96 Sensor Plate Impedance Signal time Principle of method Cleft Cleft CardioExcyte 96 Sensor Plate • Standard 96-well plate format • Optional stimulation electrode and transparent substrates) • Planar, bipolar circular gold electrodes • Supports...

Smart tools for ion channel research “We are happy to have acquired the CardioExcyte 96 from Nanion and look forward to publishing the first of many papers. We looked at several different devices on the market but were impressed by the resolution and ease-of-use of the CardioExcyte 96 and Nanion’s enthusiasm and friendly customer support. I was particularly intrigued by the pacing feature, the single electrode design giving better signal to noise ratio, the dual EFP + impedance capability, and the environmental chamber so that you can run everything on the benchtop. The new optical pacing...