Orbit 16. Instant bilayers. Just add protein

Product catalog summary

Overview: The Orbit 16 is a sophisticated platform designed for the automated formation and recording of 16 lipid bilayers simultaneously. It is engineered to enhance experimental throughput and ease-of-use in ion channel research.

Key Features:

Automated formation and re-formation of 16 lipid bilayers.
Parallel recordings from 16 individual bilayers.
Compatible with existing amplifiers such as Triton, EPC 10, and Axopatch.
Low noise, high bandwidth recordings with a resolution of less than 1 pA at 10 kHz bandwidth.
Supports both painted (MECA) and solvent-free (GUV) bilayer types.
Average bilayer stability of 6 hours.

Technical Specifications:

Sample volume requirement is approximately 150 µl per compound.
Recording chips available: GUV (Nanion) and MECA (Ionera).
Substantial increase in throughput due to parallel recording capabilities.

Applications and Benefits:

Facilitates rapid data generation and high-quality single-channel recordings.
Enables efficient research on DNA nanodevice-membrane interactions and pore-forming proteins.
Reduces the learning curve for high-quality bilayer recordings, beneficial for academic settings.

Testimonials:

Dr. Stefan Howorka from University College London highlights the Orbit 16's ability to boost scientific output and ease of use.
Dr. Friedrich Simmel from Technical University of Munich emphasizes the platform's efficiency in generating high-quality recordings of synthetic DNA membrane channels.

Contact Information: The document provides contact details for Nanion Technologies and its distributors across various countries including Germany, USA, Russia, India, Singapore, Taiwan, Japan, China, and Korea.

Catalog excerpts

Orbit 16. Instant bilayers. Just add protein.

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Orbit 16® Instant bilayers. Just add protein. • Simultaneous automated formation and • High flexibility and user control • Validated with a wide variety of targets re-formation of 16 lipid bilayers • 16 parallel bilayer recordings • Modular approach - two recording substrates • Substantial throughput increase • Low noise high bandwith recordings • Compatible with existing amplifiers 16 parallel gramicidin recordings 2. Analyzed & averaged data Press one button and obtain 16 lipid bilayers Bilayer recordings typically mean tedious waiting for bilayer formation, protein reconstitution and eventually...

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Orbit 16. Instant bilayers. Just add protein-3

simultaneous recordings: automated formation of bilayers recording chips: GUV (Nanion) & MECA (Ionera) sample volume: compatible amplifiers: average bilayer stability: high resolution recordings: supported bilayer types: painted (MECA) and solvent free (GUV) Take the pain out of painting! Ionera's MECA-chip supports automated bilayer formation through remotely actuated painting (Ionera-SPREAD). Lipid bilayers are formed on an array of 4 x 4 circular microcavities in highly inert polymer. Each integrated Ag/AgCl-electrode. The bilayers can be easily and repeatedly zapped and re-formed in an automated...

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Orbit 16. Instant bilayers. Just add protein-4

Smart tools for ion channel research “Within our research on the CsgG channel, Nanion’s Orbit 16 -combined with Ionera's MECA Chip technology- has substantially boosted our scientific output. The outstanding research tool is easy to handle and speeds up the parallel generation of 16 bilayers. By increasing the throughput of single-channel current recordings, it is a breakthrough in the biophysical analysis of pore forming proteins. Within approximately one week’s worth of lab time, we had the data needed for the recent paper in Nature. This would have been hard to achieve using conventional serial...

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