Catalogs >
Nanion Technologies >
The Patchliner

The Patchliner
4Pages

Catalog excerpts

The Patchliner. Because quality does matter.

The Patchliner Electrophysiology in the fast lane • Premium data quality and GW seals • Whole cell and single channel recordings • Unprecedented flexibility and user control • Voltage- and ligand-gated channels • High success rates • Primary cell and stem cell recordings • Voltage and current clamp recordings • Advanced temperature control • Fast solution exchange • Dynamic clamp 2. Analyzed & averaged data Press one button and walk away – 48 cells in one run The Patchliner is a fully automated bench-top patch clamp platform, recording from up to eight cells s imultaneously with GΩ seals....

Open the catalog to page 2

chip resistance: 2 MΩ (customized resistances available) seal resistance: series resistance: liquid consumption: perfusion time constant: minimum exposure time: whole cell stability: successful whole cell recording: 70 - 90 % (consistent between cell lines) Best of all worlds: throughput, performance, versatility c ardiomyocytes – it’s your choice! Current clamp Control 10 µM Nifedepine Control Control Dynamic clamp -93 pA constant current 200 pS/pF 300 pS/pF 400 pS/pF 500 pS/pF 600 pS/pF 700 pS/pF Cells courtesy of NCardia. Technical Specifications The Patchliner platform includes: •...

Open the catalog to page 3

Smart tools for ion channel research “Metrion is a company specializing in ion channel drug discovery and development, and we have invested in Patchliners because their flexibility and adaptability allow us to utilise this technology to meet the differing needs of our various screening projects. The targets we study require high quality electrophysiological recordings, and we have found that the Patchliner can deliver such output with a high success rate for a range of different ion channels and h eterologous cell lines. Nanion has been extremely helpful in customizing the software to fit...

Open the catalog to page 4