Cardiac Markers

Cardiac Markers

Cardiac Markers

Product catalog summary
Overview: Nanjing RealMind Biotech Co., Ltd. specializes in cardiac markers for diagnosing and managing cardiovascular diseases (CVDs). Their tests are used for diagnosis, risk stratification, monitoring disease progression, prognosis, and guiding treatments. The tests are compatible with the Realmind MCL60 analyzer, which is compact and user-friendly.
Key Features of Assays:
  • Comprehensive cardiac test options for myocardial infarction, chest pain, heart failure, and atherosclerosis.
  • Direct loading of original sample tubes with 8 sample positions and 20 reagent positions.
  • High throughput of 144 tests per hour with a small footprint of less than 0.38m².
  • Utilizes direct chemiluminescence immunoassay with acridinium ester label.
  • High sensitivity with 1 pg/mL detection and repeatability CV≤3%.
Biomarkers and Their Applications:
  • High-sensitivity Cardiac Troponin (hs-cTnT and hs-cTnI): Essential for diagnosing acute coronary syndrome (ACS) as per 2023 ESC guidelines.
  • Myoglobin: Sensitive marker for acute myocardial infarction (AMI), used alongside troponins or CK-MB.
  • Creatine Kinase MB Isoenzyme (CK-MB): Important for diagnosing AMI, with peak levels indicating severity.
  • BNP and NT-proBNP: Key indicators for heart failure diagnosis and prognosis, recommended by 2022 AHA/ACC/HFSA guidelines.
  • ST2: Predicts cardiovascular outcomes in heart failure, aiding in risk stratification and prognosis.
  • Lp-PLA2: Predicts atherosclerotic plaque presence and guides treatment based on risk level.
  • D-Dimer: Used to rule out thromboembolic disease and assess risk in critical patients.
Performance and Specifications:
  • High correlation in performance between RealMind assays and other established assays (e.g., Roche Diagnostics).
  • Assays support serum, plasma, and whole blood samples, with specific volume and linearity ranges for each biomarker.
Contact Information: Nanjing RealMind Biotech Co., Ltd. is located in Nanjing, China. Contact details include phone number, email, and website for further inquiries.
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Catalog excerpts

Cardiac Markers-1

Cardiac Markers •hs-cTnT •NT-proBNP •CK-MB •D-Dimer REALMIND BIOTECH 丨科 FOR DIAGNOSIS 南京仁 迈生物 技 BETTER 有

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Cardiac Markers-2

RealMind cardiac tests are employed in diagnosis, risk stratification, monitoring disease course, prognosis as well as guiding treatments for cardiovascular diseases (CVDs). The comprehensive test menu includes the following 4 panels. All biomarkers support whole blood test, and are available on the Realmind MCL60 which is a compact, bench-top, and easy to use fully-auto chemiluminescence analyzer. Myocardial Infarction Chest pain Heart failure Advantage of Assays Comprehensive menu Full cardiac test options of screening for myocardial infarction, chest pain, heart failure and atherosclerosis...

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Cardiac Markers-3

hs-cTn High-sensitivity Cardiac Troponin High-sensitivity cardiac troponin (hs-cTn) tests, including hs-cTnT and hs-cTnI, has long been recognized as the most important cardiac biomarker. The latest 2023 ESC Guideline for ACS had recommended measurement of hs-cTn in all patients immediately and consecutively as part of the diagnosis algorithm. Myo Myoglobin Myoglobin is a sensitive marker of acute myocardial infarction (AMI), as it presents in both skeletal and cardiac muscle. Any damages to these muscle types result in its release into blood. The levels of myoglobin is often used in combination...

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Cardiac Markers-4

ST2 Soluble Growth Stimulation Expressed Gene 2 ST2 is a strong predictor of cardiovascular outcomes in both chronic and acute heart failure (HF). ST2 level is associated with the severity of HF. It can be used to estimate the increased risk of cardiac death, cardiovascular events and hospitalization. It adds information to other cardiac biomarkers for risk stratification, therapy guide and prognosis. Lp-PLA2 Lipoprotein-associated Phospholipase A2 Lp-PLA2 is produced by inflammatory cells and is a highly specific biomarker to predict the presence of the atherosclerotic plaque and vascular dysfunction....

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Cardiac Markers-5

Performance of Assay Performance: RealMind hs-cTnT vs. Roche Diagnostics hs-cTnT Sample: Serum Correlation R²=0.995 RealMind ST2 vs. PresageTM ST2 Sample: Serum Correlation R²=0.989 RealMind Whole Blood hs-cTnT vs. RealMind Serum hs-cTnT Correlation R²=0.999

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Cardiac Markers-6

Assay Specification hs-cTnT hs-cTnI Myoglobin CK-MB NT-proBNP Direct chemiluminescence immunoassay (acridinium ester label) Sample type ﹙D-Dimer doesn’t support serum sample) Serum, plasma, whole blood Sample volume Linearity range Nanjing RealMind Biotech Co., Ltd. 4th floor, Bldg. A5, Maple Science Park, Nanjing Economic and Technological Development Zone, Nanjing, Jiangsu, 210033 CHINA Tel: 86-25-69579511 Email: sales@realmindbi

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