Nevro Spinal Cord Stimulation Frequently Asked Questions The Nevro Senza™ system is a next generation Spinal Cord Stimulation (SCS) system. Through its clinical studies, the Nevro SCS system demonstrated a number of key benefits.2 Is the trial procedure reversible? Yes. The leads can be removed easily. • Significant reduction in difficult-to-treat pain, including severe low back pain. • ain relief without paresthesia: P Paresthesia is a buzzing sensation that conventional SCS systems generate in order to provide pain relief. Majority of patients find the buzzing sensation uncomfortable. • mproved sleep with the Nevro therapy. I Patients with Nevro SCS typically experience significant pain relief through comfortable and paresthesia-free stimulation.2 How long does it take to recover after the surgery? As with any surgery, there will be some tenderness at the location of the surgery until the skin is fully healed. This may last several days. Will I be completely pain free with the therapy? The level of pain relief can vary. The evaluation period will allow the patient to assess the therapy. What are the risks associated with procedure? All SCS systems, including the Nevro SCS system, have similar risk profile which includes risks such as infection, swelling, bleeding, and device malfunction. Can I travel with an SCS system? Traveling is simple and easy for SCS patients. If the patient needs to go through a security screening device, such as those found at the airport, he or she should request assistance to bypass the device since you have an implanted device. Consult your physician for details. References: 1. ameron T. Safety and efficacy of spinal cord stimulation for the C treatment of chronic pain: A 20-year literature review. J Neurosurg 2004; 100:S254-S67. 2. met I, Van Buyten JP, Al-Kaisy A. European Prospective Study S with the Nevro Implantable System. Presentation at North American Neuromodulation Society 2010 Meeting. Indications of Use: The Nevro Spinal Cord Stimulation System is intended to aid in the management of chronic intractable pain of the trunk and/or limbs, including unilateral or bilateral pain associated with the following: Failed back surgery syndrome, Intractable low back pain, Leg pain. Contraindications: The Nevro Spinal Cord Stimulation System should not be used if: You are unable to operate the spinal cord stimulation system, You are a poor surgical risk. Warnings, precautions and side effects: Refer to the Patient Manual prior to use and consult your physician. Nevro Corporation 4040 Campbell Avenue, Suite 210 Menlo Park, CA 94025, USA www.nevro.com © Nevro Corp. 2011. All rights reserved. 0086 PB100103 Neurostimulation System for Chronic Pain For Europe, Australia, and Asia

Overview of Spinal Cord Stimulator System The key components of a rechargeable system are leads, rechargeable pulse generator, patient remote control, and mobile charger. • he leads are thin wires that deliver precise pulses T from the pulse generator to the spinal cord. • he rechargeable pulse generator contains a T rechargeable battery and other electronics that deliver the pulses to the lead. The rechargeable pulse generator is placed surgically under the skin, usually in the buttock or the abdomen. Chronic Pain When the pain persists for a long time and continues after the healing process...