Confocal Diagnostic Microscope HEAD OFFICE Gamagori, Aichi 443-0038, Japan TOKYO OFFICE International Division 3F Sumitomo Fudosan Hongo Bldg. 35020 Albignasego (Padova), Italy General Information High Precision: Fully automated alignment and scan time is optimised (350 images in -15 sec/exam) — nine internal fixation targets for increased patient fixation stability and device performance Full Cornea Scan: Full-automatic, semi-automatic, manual mode, and customisable exams are available with the possibility to choose the corneal layers to be scanned (endothelium, epithelium, or full cornea) in one unique exam Opacity Error Free: Through the confocal principle, high quality imaging through corneal haze and opacities is possible even with the non-contact endothelial microscopy functionality — the new Z-Ring increases the stability of the exam and the reliability of the Z-Scan reference for accurate full thickness optical pachymetry, offering the ability to define the position of any corneal structure and opacity with high precision Wide Measurement Area: With the new20x lens, it's possible to image a wide field of view counting up to 1000 cells per exam — the automatic endothelial analysis displays the density as well as polimegathism and pleomorphism indexes, giving more objective data for medical assessments Medical Device Directive 93/42/EEC Caution: U.S. federal law restricts the device to sale by or on the order of a-physician or other licensed practitioner. The process of making a diagnosis shall involve an eye doctor. Manufactured by Nidek Technologies Sri, Albignasego (Padova), Italy. Specifications are subject to change for improvement without notice. Confocal Diagnostic Microscope Jw/v^ ƒ CORNEAI D'lAqNOsfics

CS4_A4eng.qxd:Layout 1 11/18/09 3:18 PM Page 3 Non-contact Tear-film Analysis — Dry Eye Under Control Automatic Cell Analysis Full Corneal and Endothelial Microscopy, plus Accurate Pachymetry Nidek’s Confoscan4 is the only instrument that combines confocal microscopy for full-thickness cornea measurements, non-contact endothelial microscopy with tear film analyzer, plus accurate pachymetry — all in one compact unit. No other confocal device offers the versatility and value of the Confoscan4. Normal tear film (20x) Severe dry eye (20x) Full Cornea Scanning — Cornea In-vivo at the Cellular Level...