Super Resolution Microscope N-SIM E Super Resolution Microscope

Explore Nano world with Nikon N-SIM E is a streamlined, affordable superresolution system that provides double the resolution of conventional optical microscopes: the same level of superb resolution as Nikon Super Resolution Microscope N-SIM. Configured with A1+ confocal microscope Simple imaging method switching The N-SIM E can be simultaneously configured with a confocal microscope system, such as the A1+ or C2+, and imaging methods can be easily switched between super resolution imaging and confocal imaging. A desired location for the SIM image can be specified in a confocal image and acquired...

The principle of the Structured Illumination Microscopy A nalytical processing of recorded moiré patterns, produced by overlaying a known high spatial frequency pattern, mathematically restores the sub-resolution structure of a specimen. Utilization of high spatial frequency laser interference to illuminate sub-resolution structures within a specimen produces moiré fringes, which are captured. These moiré fringes include modulated information of the sub-resolution structure of the specimen. Through image processing, the unknown specimen information can be recovered to achieve resolution beyond...

Objectives for super-resolution microscopes The system can be configured with either a 100x oil immersion type, which is suitable for the imaging of fixed samples, or a 60x water immersion type, which is optimal for time-lapse live-cell imaging. The SR (super resolution) objectives have been designed to provide superb optical performance with Nikon’s super-resolution microscopes. The adjustment and inspection of lenses using wavefront aberration measurement have been applied to yield optical performances with the lowest possible asymmetric aberration. CFI SR HP Apochromat TIRF 100xC Oil CFI SR...

N-SIM E supports only essential, commonly used excitation wavelengths and imaging modes while providing the same super-resolution images as the N-SIM, making it an obvious choice for individual labs. Double the resolution of conventional optical microscopes The N-SIM E utilizes Nikon’s innovative new approach to “structured illumination microscopy” technology. By pairing this powerful technology with Nikon’s renowned CFI Apochromat TIRF series 100x Oil objective (NA 1.49), the N-SIM E nearly doubles the spatial resolution of conventional optical microscopes (to approximately 115 nm*), and enables...

System diagram TI2-P-FWB-E Motorized BA filter wheel * Required when used with confocal system Specifications and equipment are subject to change without any notice or obligation on the part of the manufacturer. December 2016 ©2015-16 NIKON CORPORATION A\ WARNING TO ENSURE CORRECT USAGE, READ THE CORRESPONDING MANUALS CAREFULLY BEFORE USING YOUR EQUIPMENT WARNING-LASER RADIATION AVOID EXPOSURE TO BEAM CLASS 3B LASER PRODUCT Total Power 500mW MAX. CW 400~700nm IEC/EN60825-1 : 2007, 2014 Monitor images are simulated. Alexa Fluor and Cy are registered trademarks of Thermo Fisher Scientific, Inc. Company...