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D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS

D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS

D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS

Product catalog summary
Introduction
Nipro PharmaPackaging specializes in developing advanced pharmaceutical packaging solutions, particularly for drugs sensitive to silicone oil. With a global presence, Nipro offers comprehensive services to enhance drug safety and administration.

Product Overview
The D2F™ Pre-fillable Glass Syringe Systems are designed for biologics, ophthalmics, and vaccines that are highly sensitive to silicone oil. These syringes are silicone oil-free, ensuring compatibility with sensitive drugs and minimizing risks associated with drug-container interactions.

Key Features
  • Silicone Oil-Free Design: Both the barrel and plunger stopper are free from silicone oil, reducing the risk of drug interaction.
  • Minimized Particle Levels: Stringent inspections ensure low levels of glass particles and foreign matter.
  • Tungsten Control: Low tungsten levels and tungsten-free luer syringes reduce interaction risks.
  • Auto-Injector Compatibility: Precise dimensions and controlled needle shield ensure smooth integration with auto-injection devices.
  • Enhanced Durability: High-quality NSV51 glass and laser-based cutting improve mechanical durability.


Processability and Quality Assurance
  • Inspection: 100% in-line camera inspection for cosmetic and dimensional quality.
  • Durability: Consistent wall thickness and minimal cosmetic defects enhance durability.
  • Process Integrity: ETO indicators and air-wash systems ensure sterility and process integrity.


Specifications
  • Volume and Dimensions: Available in various sizes with specific outer diameters and needle types.
  • Materials: Made from Nipro NSV51 borosilicate glass with options for needle types and closures.
  • Safety Systems: Available with active and passive safety systems from reputable suppliers.


Conclusion
Nipro's D2F™ Pre-fillable Glass Syringe Systems offer a reliable solution for administering sensitive biologics, ensuring safety and compatibility while maintaining high standards of quality and processability.
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Catalog excerpts

D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS-1

D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS FOR BIOTECH, OPHTHALMICS, AND VACCINES HIGHLY SENSITIVE TO SILICONE OIL

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D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS-2

D2F™ Pre-fillable Glass Syringes The molecular structure of complex biologics presents challenges to pre-fillable glass syringes. Biologics are very viscous due to their molecule size which makes the administration more difficult. To ensure easy, safe, and comfortable administrations - also at home - they often are used in combination with autoinjection devices (AI). In addition, biologics are often highly sensitive to particles and extractables & leachables as they can cause drug-container interactions that might reduce the therapeutic effectiveness. It is especially silicone, used as a lubricant...

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D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS-3

Optimized processability for minimal drug loss Reduced risk of final rejects due to cosmetic or dimensional aspects 100% in-line camera inspection of cosmetic and dimensional quality (incl. consistent flange restriction) | Rigid needle shield/closure intact and straight | Minimized particle level Increased mechanical durability minimizes risk of breakage Excellent quality of NSV51 glass (consistent wall thickness, minimal cosmetic defects, e.g., stones, knots, inclusions, etc.) | Laser-based cutting for increased durability of finger flanges Reliable processability of D2F™ tubs ETO indicator...

 Open the catalog to page 3
D2F™ PRE-FILLABLE GLASS SYRINGE SYSTEMS-4

Nipro PharmaPackaging is specialized in developing and manufacturing advanced pharma packaging products and complete packaging solutions for early development drugs or the enhancement of packaging solutions for existing drugs. With a worldwide manufacturing footprint of 15 plants, multiple sales offices, and internal lab services, Nipro PharmaPackaging offers an exceptional service platform. Through our personnel, products, and services, Nipro PharmaPackaging enables you to provide a safer and healthier administration to your customers. Nipro PharmaPackaging is part of Nipro Corporation Japan,...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.