PRODUCT PORTFOLIO GLASS TUBING, PRIMARY PACKAGING, AND MEDICAL DEVICES

Strategic Business Partner F O R P R I M A R Y PA C K A G I N G A N D M E D I C A L D E V I C E S Nipro PharmaPackaging is an established market leader in the development and manufacture of primary packaging and medical devices in the pharmaceutical industry. Vertically integrated As a vertically integrated company, we draw our own premium glass tubing in multiple state-of-the-art plants worldwide. The integration of this step in-house ensures a stable supply of raw materials with a consistent high quality to our glass converting plants. Extensive Experience For over 60 years, we’ve been developing...

Global Manufacturing Network Your products are manufactured within our broad manufacturing network. We operate numerous state-ofthe-art plants in North America, Europe, and Asia enabling local supply and the possibility to source the same high-quality products from multiple sites. Comprehensive Customer Support Products and technologies constantly increase in complexity. Our comprehensive and competent support organization comprising regulatory assistance, technical support, and laboratory services will address all your inquiries quickly and efficiently. Commitment to Quality When medication...

The process of defining the right quality of your primary packaging to meet your drug product requirements is a complex process. Multiple parameters need to be considered to ensure the right match. Parameters influencing the required primary container quality Drug Complex biotech drugs require highly sophisticated packaging solutions when it comes to drug-container compatibility. (silicone amount, tungsten levels, particles, ...) Attributes that are essential when the container is combined with a device. (mechanical glass durability, dimensional aspects, ...) Any data required to confirm compliance...

With decades of experience in manufacturing high-quality glass tubing for the pharmaceutical industry, Nipro has acquired the expertise to advice you on the glass tubing that is best suited for your primary container. Fast and reliable converting-line performance Very strict cosmetic parameters Highly precise dimensional attributes Customize your glass tubing parameters to meet specific primary packaging quality and service requirements that differ from the current quality levels Meeting highest regulatory and quality requirements Customization is fully supported by an experienced and dedicated...

Pre-fillable Glass Syringes F O R P H A R M A C E U T I C A L A P P L I C AT I O N S The careful selection of raw materials and precisely-controlled manufacturing processes yield D2F ™ pre-fillable glass syringes that are made exactly for their intended applications, offering the right quality for prevailing drug products as well as challenging Biotech drugs. Optimized processability for reduced TCO Excellent drug-container compatibility Designed for reliable and safer manual administration Smooth integration into autoinjection devices Customize your syringe specifications to meet specific primary...

Syringe Size & Type Volume (ml) Staked needle Free length (inch | mm) Wall type V-bevel V-bevel V-bevel V-bevel V-bevel V-bevel Regular Regular Thin Regular Thin Ultra-thin Luer lock Staked Needles Components Needle shield Plunger stoppers Safety devices Soft needle shield Hard needle shield LInC V-OVS® Easy-turn tip cap Ribbed tip cap Standard Coated Safe’N’Sound® Novaguard® Ypsomed® Rubber components are supplied by the prevailing manufacturers of the pharmac

D2F Sterile Packaging Direct To Fill Our fully automated packaging process takes place in an ISO 7 / ISO 8 cleanroom with 100% monitoring under laminar air flow. EtO sensitive indicator on label 100% in-line camera inspection Cleaned with ionized air Nest & tub are cleaned with ionized air Washed syringes are loaded into nest & tub Covered with insert(s) and sealed with lid (Tyvek®) Sealed tub is entered into breather bag(s) and welded closed 100% camera inspection confirms each tub is correctly filled & sealed Tubs are transferred into outer boxes Outer boxes are placed on pallets and secured...

Nipro vials are characterized by precise dimensional and pristine cosmetic parameters. The carefully-controlled specifications enable a smooth integration on fill-finish lines. Our glass vials are made from high-quality glass tubing offering secure storage of drug products. Nipro’s proprietary VIALEX™ technology offers exceptional glass surface durability for highly sensitive drugs. Fast and reliable filling-line performance Outstanding drug-container compatibility Compliant with prevailing quality standards Optimized filling-line performance Customize your vial specifications to meet unique...

Crimp neck Volume (ml) Surface Ammonium sulfate treatment VIALEX ™ Screw neck Volume (ml) Ammonium sulfate treatment VIALEX ™

Unit / Bi-dose Volume (ml) Specialty vials We offer a broad range of special and customized vials such as high recovery vials, V-bottom vials, and double chamber vials.

Economical and well-proven, glass ampoules are a frequently selected primary packaging type by the pharmaceutical industry. Nipro offers a wide range of high-quality ampoules. Benefits Precisely Formed for Fill-Finish Operations Nipro ampoules are carefully monitored during the manufacturing process. The 100% in-line visual camera inspection ensures precise dimensional forming of the ampoules according to agreed quality specifications. The ampoules support quick and easy fill-finish operations. Stable Break Force Facilitates Easy Opening The force necessary to open an ampoule is an essential...

Form B Outer Ø – Body (mm) Form B Form Form Form B Form B B B Code rings Printing Surface treatment Breaking system Double Tip Double Double Double Double TipTipTipTip Fine Tip Fine Fine Tip Fine Tip Fine TipTip Form D Form Form Form D Form DDD Form C Form Form Form C Form C C C Form B | Form C | Form D | Fine Tip Ceramic (max. 2 colors) With or w/o Teflon (natural fiber brush) Color Break Ring, Open Point Cut, Scoring Ring