RENAL CARE VASCULAR ACCESS BECAUSE EVERY LIFE DESERVES AFFORDABLE CARE

Because vascular access is the gateway to quality of life, Nipro is dedicated to providing the best possible care to every vascular access. Given that the arteriovenous fistula (AVF) is the method of choice for vascular access1, special care should be taken to ensure its survival. Among others, the following needle specifications for the prevention of vascular access complications are suggested:1 • First few cannulations of a new fistula should be performed with a 17 G needle1,2,4. At a later stage, the needle gauge may be adapted to the patient’s blood flow. A lower needle gauge can withstand...

REGULAR NEEDLES • NOT MADE WITH DEHP • N O T M A D E W I T H L AT E X • G A M M A S T E R I L I Z AT I O N STANDARD, 2-PACK, SINGLE NEEDLE O U T S TA N D I N G Q U A L I T Y A N D P E R F O R M A N C E F R O M Y E A R S O F E X P E R I E N C E A N D R I G I D M A N U FA C T U R I N G C O N T R O L ULTRA SHARP AND SILICONIZED 3-BEVEL NEEDLE OVAL-SHAPED BACK-EYE Ensures smooth and optimal puncture and prevents vessel trauma Optimizes blood flow and minimizes the risk of aspiration to the vessel wall on the arterial needle ULTRA-THIN NEEDLE WALL Guarantees an optimal blood flow Indicates the bevel...

STANDARD, 2-PACK, AND SINGLE NEEDLE ADVANTAGES • Easy to handle AVF needles • Smooth cannulation with ultra sharp needle • Optimal blood flow SPECIFICATIONS Standard Needles Single Needles Arterial Needle* Venous Needle* 1 Arterial Needle* + 1 Venous Needle* Size Needle Length Tube Length Color (Gauge) (mm) (mm) * Needles with turnable wings. Arterial and venous needles are also available with fixed wings instead of turnable wings. Please contact your local office for other specifications, order quantities, and availability. SINGLE NEEDLE

ULTRA SHARP AND SILICONIZED 3-BEVEL NEEDLE Ensures smooth and optimal puncture and prevents vessel trauma SIDE HOLES Optimizes blood flow and minimizes the risk of aspiration to the vessel wall ULTRA-THIN CATHETER WALL Guarantees an optimal blood flow Facilitates the recognition of gauge size SOFT FLEXIBLE TUBING Eases the clamping during the bloodline connection/disconnection TAPERED LUER Warrants a safe and easy connection/disconnection with bloodlines

CATHETER NEEDLE ADVANTAGES • Plastic fistula needles may prevent vascular access complications1 • Safe cannulation during fistula maturation1 • Decreased risk of perforation1 • Greater patient mobility • Better option for patients allergic to metal SPECIFICATIONS AVF Catheter Needle Size (Gauge) Please contact your local office for other specifications, order quantities, and availabil

SAFETY NEEDLES FUNDAMENTAL PROTECTION AGAINST NEEDLESTICK INJURIES (NSI) Every year, healthcare professionals are affected by needlestick and sharps injuries. The World Health Organization estimates that 3 of the 35 million healthcare professionals worldwide are exposed to bloodborne pathogens each year as a result of these injuries.3 Almost 50% of injuries are not reported which leads to a significant under-estimation.4

Since 1 in 5 patients in dialysis centers globally are considered “at risk”for HIV and Hepatitis B and C, NSI are a major occupational hazard for both healthcare professionals and hospitals.5 EXTRA PRESSURE ON HEALTHCARE PROFESSIONALS • After a NSI and before contamination is confirmed or denied: — Stress and decreased productivity • For those who contract a disease as a result of their injury: — Lifelong consequences — Physical and emotional adjustment — Financial burdens — Inability to continue working in the healthcare profession in some cases ADDITIONAL BURDENS FOR HOSPITALS • Costs for testing...

SAFETY NEEDLES • NOT MADE WITH DEHP • N O T M A D E W I T H L AT E X • G A M M A S T E R I L I Z AT I O N OVAL-SHAPED BACK-EYE ULTRA SHARP AND SILICONIZED 3-BEVEL NEEDLE Ensures smooth and optimal puncture and prevents vessel trauma Optimizes blood flow and minimizes the risk of aspiration to the vessel wall on the arterial needle ULTRA-THIN NEEDLE WALL Guarantees an optimal blood flow Indicates the bevel position on the needle with turnable wings TURNABLE OR FIXED COLOR-CODED WINGS Facilitates the recognition of gauge size TEXTURED WINGS Provides secure grip during needle manipulation SAFETOUCH...

SAFETOUCH™ AVF NEEDLE FEATURES • Reduced risk of needle stick injury • Non-reversible mechanism • Active safety feature using a one-handed technique • Secured locking confirmed by an audible and tactile click • Unique locking mechanism SAFETOUCH™ AVF NEEDLE SAFETY MECHANISM • Hold down the wing protector and/or the wings with one hand • With the other hand, release the lock by pressing in both sides of the stopper • Slide the stopper forward until it becomes completely locked with an audible or tactile click SPECIFICATIONS Size Needle Length (Gauge) (mm) Arterial Needle* Venous Needle* * Needles...

SAFETY NEEDLES • NOT MADE WITH DEHP • N O T M A D E W I T H L AT E X • G A M M A S T E R I L I Z AT I O N SAFETOUCH TULIP™ ERGONOMIC PROTECTION OVAL-SHAPED BACK-EYE ULTRA SHARP AND SILICONIZED 3-BEVEL NEEDLE Optimizes blood flow and minimizes the risk of aspiration to the vessel wall on the arterial needle ULTRA-THIN NEEDLE WALL Ensures smooth and optimal puncture and prevents vessel trauma Guarantees an optimal blood flow TAPERED LUER Warrants a safe and easy connection/disconnection with bloodlines Indicates the bevel position on the needle with turnable wings TURNABLE OR FIXED COLOR-CODED...

SAFETOUCH TULIP™ FEATURES • Reduced risk of needle stick injury • Non-reversible mechanism • Active safety feature using a one-handed technique • Secured locking confirmed by a tactile click • Unique patented locking mechanism* SAFETOUCH TULIP™ SAFETY MECHANISM • Hold down the wing protector and/or the wings with one hand • With the other hand, slide the Tulip needle protector forward until two petals of the Tulip needle protector tip are positioned over the flattened wings • Grasp the tubing at the base of the Tulip needle protector • Pull on the tubing while pushing the Tulip needle protector...