Catalog excerpts
Bioactive Bone Substitute Synthetic Bone Substitutes Bioactive Glass Technology
Open the catalog to page 1BIOMATERIALS FOR TRUE BONE REGENERATION NORAKER® has been involved in biomaterial development since 2005. It’s today an innovative manufacturer of medical implants for bone regeneration, with its core technology: the BIOACTIVE GLASS, a synthetic bioresorbable ceramic. The bone substitutes Activioss ® Granules and Activioss® Putty are made of bioactive glass. This ceramic is composed of Silicium, Calcium, Sodium and Phosphorous, minerals naturally present in the human body. The natural composition allows an excellent biocompatibility. 1 2 3 The Bioactive glass has been classified by Dr Larry...
Open the catalog to page 2Activioss® range : Injectable Putty and Granules Injectable Putty To mix with patient’s blood, patient’s bone or saline solution 1. Easy to use Granules: Very cohesive and hydrophilic when mixed with serum, blood or autologous bone. Injectable Putty: Ready to use ,can be injected through the syringe. 2. Ionic exchanges At 14 days: formation of an active biological mineral layer of calcium phosphate, with similar composition and structure as human bone.1 3 5 3. Activation phase At 21 days: The increased concentration of minerals improves the differenciation and proliferation of osteoblasts...
Open the catalog to page 3Did you know? Bone substitutes are classified into an Index of Bioactivity.8 Matrix for the bone colonization + Stimulation of stem cells Matrix for the bone colonization Adhesion and Proliferation of mesenchymal stem cells hMSC on Activioss .9 (in vitro study) ® Stem cells adhesion ® on the surface of Activioss (dark dots) Multiplication and differentiation of the stem cells (dark spider web) Extracellular matrix and natural hydroxyapatite in formation Dense extracellular matrix; cells differentiated in osteoblasts Blood Vessel Biomaterial 4. Bone Regeneration Osteoid At 6.5 months,...
Open the catalog to page 4Clinical Results Examples 1: Sinusal bone augmentation using bioactive glass and bone flap repositioning Baly Private clinic Villeurbanne - France A retrospective study evaluated the success rate of implantation after sub-sinusian bone augmentation performed by the modified Tatum technique with repositioning of the bone flap and using the bioactive glass 45S5 (Activioss®) as a bone substitute. The surgical technique is described in an iconographic case: Fifty-eight consecutive cases in fifty-eight patients have been operated with this technique. One hundred eleven dental implants were...
Open the catalog to page 5Granule size Activioss Injectable Putty ACT-IP1.0 ACT-IP2.5 It is indicated in adults and children (oral surgery only) in case of loss or lack of bone substance for bone defects of traumatic, pathological or surgical origin, in dental/ oral surgery when autologous solutions are not applicable or sufficient.10 Tsigkou, O. et al. Biomaterials. 2009;30:3542-50 Oonishi, H. et al. J. Biomed. Mater Res. 2000;51:37-48. Jones, J.R. Acta Biomaterialia. 2013;9:4457-4486. Xynos, I.D. et al. Calcif Tissue Int. 2000;67:321-9. Hench, L.L. J. Mater Sci: Mater Med. 2006;17:967-978. Jell, G. et al. J Mater...
Open the catalog to page 6All NORAKER catalogs and technical brochures
-
Sports Medicine
12 Pages