Synthetic Bone Substitutes Bioactive Glass Technology

BIOMATERIALS FOR TRUE BONE REGENERATION NORAKER® has been involved in biomaterial development since 2005. It’s today an innovative manufacturer of medical implants for bone regeneration, with its core technology: the BIOACTIVE GLASS, a synthetic bioresorbable ceramic. GlassBone™ Substitutes are made of bioactive glass. This ceramic is composed of Silicium, Calcium, Sodium and Phosphorous, minerals naturally present in the human body. The natural composition allows an excellent biocompatibility. 1, 2, 3 The Bioactive glass has been classified by Dr Larry Hench Class A bone substitute, whereas...

GlassBone™ range : Injectable Putty and Granules GlassBone'Granules To mix with patient's blood, patient's bone or saline solution 1. Easy to use Granules: very cohesive and hydrophylic when mixed with saline serum, patient blood or autologous bone. Injectable Putty: Ready to use, can be injected through the syringe. At 14 days: formation of an active biological mineral layer of calcium phosphate, with similar composition and structure as human bone. 1 3, 5

Did you know? Bone substitutes are classified into an Index of Bioactivity (only demonstrated by in-vitro study).8 Bioactivity study - In vitro evaluation for apatite-forming ability. 10 (in vitro study) (a) GlassBone™ Granules (b) GlassBone™ Injectable Putty SEM images of (a) GlassBone™ Granules 05.1 and (b) GlassBone™ Injectable Putty a magnification of x50 (left) and X 10,000 (right) after 28 days of immersion in SBF (testing according to ISO 23317:2014). The surface of the granules presents cracks at x50 and needle-like structures at X 10,000. This is characteristic of hydroxyapatite formation....

Clinical Results Examples 1_ C linical and radiographic evaluation of bioactive glass in posterolateral cervical or lumbar spinal fusion. European Journal of Orthopaedic Surgery & Traumatology (2019) Barrey C, Broussolle T METHOD: Retrospective case series. 30 consecutive patients with indications for a posterolateral spinal fusion procedure were operated. Appropriate decompressive surgery was performed with subsequent fixation using posterior instrumentation as appropriate and filled with bioactive glass. GlassBone™ Granules (1 – 3.15 mm) were mixed with local autograft harvested from the surgical...

Bioactive Bone Substitutes Granule size GlassBone™ Granules Loss or lack of bone substance for bone defects of traumatic, pathological or surgical origin when autologous solutions are not applicable or sufficient in orthopedics, neurosurgery, cranio maxillo facial and otorhinolaryngology surgery in children and adult population. Main indications: • ORTHOPAEDIC SURGERY • SPINAL SURGERY GlassBone™ Injectable Putty 2. Oonishi, H. et al. J. Biomed. Mater Res. 2000;51:37-48. 3. Jones, J.R. Acta Biomaterialia. 2013;9:4457-4486. 4. Xynos, I.D. et al. Calcif Tissue Int. 2000;67:321-9. 5. Hench, L.L....