Cleanroom Conditions for In-Office Intravitreal Injections with Operio Mobile Laminar Air Flow Achieve ISO 5 Sterility for Maximum Infection Control in Ophthalmology Clinics The Need for Ultra-Clean Air in Intravitreal Injection (IVI) Procedures Operio is a mobile, ultra-clean air purification system that directs focused laminar airflow over the patient’s eye and instrument table. This uninterrupted ISO 5 sterile airflow prevents airborne contaminants from entering the injection site, effectively transforming any standard ophthalmic office into a controlled cleanroom environment. A recent study comparing the microbial load in outpatient clean rooms (OCRs) versus hospital-based operating theaters (HOTs) demonstrated that using a mobile laminar airflow (LAF) system in an OCR significantly reduced air contamination to levels comparable to those in a hospital OR. Intravitreal injections (IVIs) are a critical treatment for retinal diseases such as age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusions. While these procedures are routine, they carry a small but serious risk of infection, with endophthalmitis being the most severe complication. Maintaining a sterile, contamination-free environment is essential to ensuring patient safety and reducing the likelihood of postoperative infections. However, many outpatient ophthalmic clinics lack hospital-grade ventilation systems, increasing the risk of airborne contamination during IVIs. Traditional hospital operating theaters (HOTs) provide a controlled, sterile environment, but requiring every IVI to be performed in an HOT can be impractical, costly, and inefficient. The Operio Mobile Laminar Air Flow system provides a game-changing cleanroom-level sterility solution for inoffice IVIs, eliminating 99.995% of airborne bacteria and viruses without the need for major renovations or high-cost infrastructure. read more Operio Focused Laminar Air Flow System: The compact, mobile unit is positioned next to the patient, delivering uninterrupted ISO 5 sterile airflow directly over the patient’s eye and instrument table. Contact Information Normeditec Italy, Germany Email: [email protected] Phone Support: Italy: +39 348 730 24 45 Germany: +49 7139 2090859 WhatsApp Support: Italy: +39 348 730 24 45 Germany: +49 176 62 13 16 34 Website: www.normeditec.com Worldwide Delivery & Remote Support: We deliver globally and offer video call support to assist you with advanced aseptic solutions. Contact us today to enhance your practice with cutting-edge sterile airflow technology

Key Advantages of Operio for In-Office Intravitreal Injections ISO 5 Sterility in Just 2 Minutes – Operio rapidly establishes cleanroom-level air quality, minimizing microbial contamination before, during, and after injections. Eliminates 99.995% of Airborne Bacteria and Viruses – Advanced HEPA H14 filtration ensures a sterile field, significantly reducing the risk of post-injection endophthalmitis. Ideal for High-Volume IVI Clinics – Ensures fast turnover times and maintains aseptic conditions between procedures, increasing efficiency and patient safety. Cost-Effective & Plug-and-Play Installation...

Limitations of Conventional Operating Room Ventilation Systems Traditional ceiling-mounted ventilation systems often fail to provide consistent protection over the surgical field during procedures. Despite being designed to maintain a sterile environment, their effectiveness is frequently compromised due to airflow obstructions from: Surgical lights Ceiling-mounted microscopes Operating room staff movement Traditional vertical airflow systems in operating theatres can increase the risk of bacterial contamination by directing air over the surgical team’s heads and towards the open surgical site....

y Budget-Friendly: Saves hospitals and clinics thousands by eliminating the need for costly air purification systems y Plug & Play Setup: Runs on standard power sockets—perfect for outpatient and ophthalmic centers y Adjustable Instrument Table: Available in 45cm, 60cm, and 75cm sizes for diverse surgical needs y Energy-Efficient: Uses only 290W, reducing operational costs significantly y Silent Performance: Ensures a distraction-free surgical environment

Compact and Flexible Solutions for Sterile Operating Room Condition The Operio Mobile Laminar Air Flow system stands out for its compact design and versatility, making it an efficient solution even in the smallest operating rooms. . Adjustable Instrument Table for Every Surgical Need: Available in three sizes: •45 cm – Ideal for minor procedures. •60 cm – Suitable for standard surgeries. •75 cm – Perfect for complex procedures requiring extensive instrumentation. Removable functionality – Eliminates the need for an additional instrument table. User-Friendly Operation: Electric height adjustment...