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ihcDirect® GFAP Kit

ihcDirect® GFAP Kit
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ihcDirect® GFAP Kit

Product catalog summary
Product Overview:
The ihcDirect® GFAP Kit is designed for tissue-based diagnostics, specifically for identifying glial fibrillary acidic protein (GFAP) in central nervous system cells. It utilizes a polymerized horseradish peroxidase (pHRP) labeled GFAP antibody (Clone R246) for immunohistochemistry (IHC) tests on formalin-fixed, paraffin-embedded (FFPE) or frozen tissue sections.
Specifications:
  • Catalog Number: K42002-XXX
  • Package Sizes: -005 for ~50 tests, -010 for ~100 tests
  • Antibody Type: Rabbit
  • Storage Instructions: Store at 4°C, do not freeze
  • Intended Use: For In Vitro Diagnostic Use
Intended Use and Application:
The kit is intended for laboratory use to qualitatively identify GFAP in tissue sections using light microscopy. It is applicable for both FFPE and frozen tissues. The results should be interpreted by a qualified pathologist or physician, considering the patient's clinical history and other diagnostic tests.
Summary and Explanation:
The GFAP Kit is optimized for detecting GFAP, a 52kD intermediate filament protein, in various central nervous system cells such as astrocytes and ependymal cells. It is also applicable in the peripheral nervous system and can aid in identifying astrocytomas and ependymomas in neoplastic tissues. The kit includes an ihc Blocker to reduce background staining and uses 3,3’diaminobenzidine (DAB) as a chromogen.
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Catalog excerpts

ihcDirect® GFAP Kit-1

Revolutionizing tissue-based diagnostics ihcDirect® GFAP Kit Anti-Human GFAP (Clone R246) Glioblastoma Using Frozen Tissue Catalog Number: Brain Using FFPE Tissue Package Size: -005: For ~50 IHC Tests using frozen or FFPE tissues (XXX) -010: For ~100 IHC Tests using frozen or FFPE tissues Antibody: Store at 4°C upon receiving. DO NOT FREEZE. ihcDirect GFAP (glial fibrillary acidic protein) is a polymerized horseradish peroxidase (pHRP) labeled GFAP (R246) antibody intended for laboratory use to qualitatively identify by light microscopy the presence of GFAP, which is expressed in several types of central nervous system cells including astrocytes and ependymal cells, in sections of formalin-fixed, paraffin-embedded (FFPE) tissue sections or frozen tissue sections using immunohistochemistry (IHC) test method. The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests and proper controls interpreted by a qualified pathologist and/or physician. This conjugate has been pre-diluted and optimized for IHC use without further dilution. Summary and Explanation: ihcDirect® GFAP Kit (Clone R246) immunohistochemistry (IHC) reagent is for use on frozen and formalin-fixed-paraffinembedded tissues. Clone R246 antibody reacts with GFAP (glial fibrillary acidic protein), which is a 52kD intermediate filament protein, that is expressed in several types of central nervous system cells including astrocytes and ependymal cells. In the peripheral nervous system, GFAP has been demonstrated in Schwann cells, enteric glial cells and satellite cells of human sensory ganglia. In neoplastic tissues, the antibody may be useful for the identification of astrocytomas and ependymomas. The ihc Blocker provided in the kit used prior to applying GFAP conjugate can reduce background and nonspecific staining. Chromogen 3,3’diaminobenzidine (DAB) is used in this kit. www.novodiax.com [email protected] [email protected] 3517 Breakwater Ave Hayward, CA 94545, USA Phone: +1 (888) 439-2716 EMERGO EUROPE Prinsessegracht 20 2514 AP The Hague The Netherl

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