Introduction
ManuMix® is a patented sterile mixing system designed for the manual mixing of bone cement with low to medium viscosity, facilitating its transfer into syringes for clinical applications. Manufactured by OSARTIS GmbH, the system ensures a homogeneous mix and clean transfer of bone cement.

Components
The system comprises three main parts:

• Mixing cup
• Transfer insert with Luer connection
• Spatula

Properties

• Easy handling and safe transfer process
• Reduced air entrapment due to tight Luer connection
• Optimal removal technique minimizing cement residues
• Delivered sterile in a soft blister

Material
The ManuMix® system is constructed from polypropylene, compatible with PMMA bone cement.

Bone Cement Volume
When mixed, BonOs® Inject components yield a PMMA bone cement volume of 25 ml. The available volume for injection varies based on temperature, mixing system, syringe type, and filling time.

Procedure

1. Mix bone cement using the spatula provided.
2. Connect the syringe to the Luer connection of the transfer insert.
3. Transfer the bone cement cleanly into syringes.

Available Cement Volume by Syringe Type
The table below summarizes the mean available cement volume for different syringe types when using BonOs® Inject with ManuMix®:

Syringe Type	Available Cement Volume
1 ml	20 ml
3 ml	22 ml
6 ml	23 ml

Conclusion
ManuMix® offers a reliable and efficient solution for the preparation and transfer of bone cement in clinical settings, ensuring minimal waste and optimal application.