General overview FlowOx™ FlowOx™ is a novel medical device for the treatment of peripheral arterial disease (PAD) related problems such as pain, reduced walking distance and chronic ulcers. The use of FlowOx™ is comfortable and easy: the system generates an intermittent negative pressure (INP) that stimulates the blood circulation in the lower legs and feet, thus improving the blood flow and oxygen supply. FlowOx™ advantages • Non-invasive, safe and easy to use • Suitable for home use • Can be used in addition to surgical intervention or where surgery is contraindicated • May be used on limbs with existing wounds if they are bandaged FlowOx™ patient target group • Peripheral arterial disease (PAD), • Diabetic and non-diabetic arteriopathic foot and leg ulcers, • Intermittent claudication and rest pain, • Foot and lower leg ulcers of mixed aetiology associated with immobility such as paraplegia f

FlowOx™ usage For an optimal therapeutic effect, it is recommended using the device for 2 hours per day, which can be easily integrated into everyday life (e.g., one hour in the morning and one hour in the evening). If FlowOx™ is used as recommended, patients can expect a reduction in pain and possibly visual improvements in the wound healing within 2-3 weeks. In addition, most patients show positive long-term effects, e.g., lasting pain reduction, increased walking distance, improved blood flow and potentially complete wound healing. In order to ensure compliance to the therapy, it is important...