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Information for Healthcare Professionals
Information for Healthcare Professionals
Peripheral Arterial Disease (PAD) is a condition characterized by reduced blood circulation in the limbs, leading to pain, chronic wounds, and potential amputations. It affects approximately 200 million people globally and is often undiagnosed until severe, increasing the risk of limb amputation.
FlowOx™ is a novel, non-invasive medical device designed to treat PAD-related issues such as pain, reduced walking distance, and chronic ulcers. It enhances blood flow and oxygenation in the lower limbs through pulsating negative pressure, which dilates arterioles and increases the arteriovenous pressure gradient.
- Non-invasive and easy to use, suitable for home use.
- Can be used alongside surgical interventions or when surgery is contraindicated.
- Applicable on dressed wounds.
- Smoking history
- Hypertension
- Age over 50
- High cholesterol
- Diabetes Mellitus
- Symptomatic treatment: pharmaceutical and wound care.
- Surgical interventions: bypass, stent, angioplasty.
- FlowOx™ as a baseline therapy, complementing existing treatments.
FlowOx™ uses Intermittent Negative Pressure (INP) to stimulate blood circulation, improving endothelial function and blood flow even in small vessels. Regular use can lead to long-term benefits such as pain reduction and improved wound healing.
For optimal results, FlowOx™ should be used for 2 hours daily, split into convenient sessions. Patients may notice pain reduction and wound improvement within 2-3 weeks.
- Patients with intermittent claudication or critical limb ischemia.
- Patients at risk of amputation due to PAD.
- Patients with upcoming vascular interventions or amputations.
- Patients with acute and chronic arterial/mixed ulcers.
For orders and inquiries, contact Otivio AS at [email protected] or +49 151 28 27 35 36.
Catalog excerpts
Information for Healthcare Professionals
Open the catalog to page 1
Peripheral artierial disease (PAD) is a medical condition where the blood circulation in the limbs is reduced and leads to pain, chronic wounds and amputations. PAD affects the health and quality of life of an estimated 200m people worldwide and is projected to rise disproportionately in the coming years.1 Risk Factors Smoker or used to smoke The healthcare cost of a PAD patient is 3-4 times higher p.a. compared to the average adult control without PAD. High cholesterol Diabetes Mellitus Health Pain Comorbidity Mortality Amputation Treatment Symptomatic treatment: • Pharmaceutical • Wound care...
Open the catalog to page 2
1 in 5 people over 50 have some degree of PAD.6 It’s more common in men than in women.7 Around 2% of people with intermittent claudication will eventually undergo amputation, making PAD one of the biggest causes of lower-limb amputation.8 Approximately 5000 major amputations are undertaken in England every year, with over 90% being PAD related.9 FlowOx™ - Mode of Action Intermittent Negative Pressure (INP) Translating Acute Effects into Long Term Effect Acute Effect on Blood Flow First 1-3 seconds: Rapid increase of transmural pressure during -40 mmHg phase. Initiation of transient vasodilation,...
Open the catalog to page 3
The Effect Intermittent negative pressure (INP) stimulates the micro- and macrocirculation of blood in the extremities and when applied regularly, it will revitalise the natural endothelial function - similar to the way muscle strength and function can improve through regular exercise. INP will work even in the smallest blood vessels and thereby can improve function and blood flow to the extremities and skin.4, 5, 10 An unmet medical need... Current treatment strategies for PAD are often limited, inadequate and symptomatic, resulting in poor outcomes. FlowOx™ offers a baseline intervention that...
Open the catalog to page 4
Ordering information For orders, deliveries and general enquires please contact Otivio AS: Tel.: +49 151 28 27 35 36 E-Mail: [email protected] References: 1. Medpage Today, August 2, 2013. 2. All-Part Parliamentary Group, 2016. Saving limbs, saving lives: patient access to technologies for the diagnosis and treatment of peripheral arterial disease. 3. Scully, RE., DeBord Smith, A. et al. 2016. Annual Health Care Expenditures in Individuals with Peripheral Arterial Disease, Journal of Vascular Surgery, Vol 64(4), 1180–1181. 4. Sundby Ø. et al., 2017. Blood flow in PAD patients enhanced by FlowOx....
Open the catalog to page 6All Otivio catalogs and technical brochures
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