How the T-SPOT.TB test helps you1 How the T-SPOT.TB test works based on the proprietary T-SPOT technology1 • Identifies a high percentage of infected subjects and is the only interferon- gamma release assay (IGRA) with sensitivity of 98.8%. • The only IGRA that separates cells from whole blood and standardises the number of these cells used in each patient test, reducing the risk of false- negative and indeterminate test results. • Specificity above 99%. False-positives are rare with the T-SPOT.TB test, so unnecessary chemoprophylaxis and follow-up is minimized. • Is unaffected by BCG vaccination...

Testing of patients with conditions that weaken the immune system and increase the risk for latent TB reactivation, including: HIV infection, treatment with immunosuppressants, including anti-TNF-α therapy and high-dose steroids, chronic renal disease and cancer chemotherapy. • Targeted testing of high-risk populations including: Close contacts, migrants, prisoners and patients suspected of TB. • Pre-employment and regular screening of healthcare professionals. REFERENCES 1 T-SPOT.TB Package Insert (PI-TB-IVD-UK-V3) 2 Year to date (1/12/15) 2015 data at Oxford Diagnostic Laboratories, UK T-SPOT...