Introduction
The LIVERguard™ System is a cutting-edge solution for donor liver preservation and transport, offering a new standard in the field. It is the only FDA-cleared and CE-marked hypothermic liver preservation device available, designed for consistent and measurable organ transport.

Specifications
The system ensures stable preservation with a lightweight shipper validated for maintaining a consistent thermal environment for over 40 hours. It employs a precision cooling system using proprietary SherpaCool™ phase change technology to prevent excessive temperature reduction.

Monitoring and Connectivity
The LIVERguard™ System features real-time monitoring and data reporting through the Paragonix App via Bluetooth®, facilitating communication among donor and recipient transplant teams.

Protection Features
The device includes a mechanically isolated protection system with a rigid tray and rack structure that encapsulates a triple bag isolation system, providing enhanced protection from physical and thermal trauma.

Clinical Evidence and Recommendations
Clinical studies indicate that sub-zero temperatures can cause indissoluble particles in preservation solutions, potentially leading to thrombosis and vessel occlusion. The LIVERguard™ System addresses these issues by avoiding freezing injuries and ensuring compliance with UNOS 16.3 temperature-controlled packaging guidelines.

Limitations of Ice Storage
Traditional ice storage methods reach temperatures below 1°C within 40 minutes, contributing to early allograft dysfunction and lower graft survival rates. The LIVERguard™ System offers a more controlled alternative, reducing cold ischemic time and improving outcomes.

Conclusion
The LIVERguard™ System represents a significant advancement in liver preservation, providing predictable, repeatable, and measurable results, moving beyond the limitations of ice storage.