Easy One-Instrument Analysis of Microsatellite Instability MicroSight® MSI is a new and simple way of characterizing microsatellite instability (MSI) status of tumors. The analysis takes less than 90 minutes, making it useful in treatment guidance. The analysis provides an unambiqous answer, completely objective, unbiased and independent on user-experience. Fast and simple real-time PCR based analysis of microsatellite instability Purify DNA Analyse data MicroSight® MSI workflow. Only three fast and simple steps are needed for the analysis of microsatellite instability using PentaBase’s MicroSight® MSI technology. The method is based on high-resolution melt analysis and gives a clear and reliable answer, providing unbiased results. Easy evaluation of microsatellite instability Completely unbiased analysis - provides a yes or no answer No trained staff needed Low-cost instrument More information at www.pe

MicroSight MSI relies on PentaBase’s proprietary INA® technology that enables highly sensitive detection of microsatellite instability status. The method is based on high-resolution melt and runs on a single instrument, lowering hands-on time and duration of entire analysis. Evaluation of MSI-H status is performed on the basis of differences in melt curves of probes binding to the amplified microsatellites. 100% correlation with fragment analysis No inter-lab and inter-instrument variation Known loci - BAT25, BAT26, NR22, NR24 and MONO27 Can be used with both paired samples and a universal reference...