Detect down to one copy of KIT D816V in 100 ng DNA sample The PlentiPlex™ Mastocytosis assay combines the high selectivity of SensiScreen® FFPE assays with the extreme sensitivity of SensiScreen® Liquid, enabling detection of single copy mutants in concentrated DNA samples. Mastocytosis is the common term for a heterogenous group of diseases characterized by abnormal accumulation and growth of neoplastic mast cells in tissue and organs. KIT D816V mutation is almost always present in Mastocytosis patients and this somatic alteration is among the WHO criteria for diagnosis of mastocytosis. PlentiPlex® Mastocytosis recognizes down to a single copy of mutated DNA in 100 ng WT DNA (LOD 0.003%) PlentiPlex® Mastocytosis workflow Purify DNA from biopsy Add purified DNA to reference and assay Ready-to-use tubes of PlentiPlex® Mastocytosis PlentiPlex™ Mastocytosis assay run on a MyGo Pro qPCR instrument. 100 ng WT DNA and 50 ng WT DNA spiked with 2 copies of KIT D816V mutant was PlentiPlex® Mastocytosis offers a simple, efficient and sensitive analysis More information at www.pentab

Five loci in one vial - three different Pentaplex panels PlentiPlex™ MSI assays are intended for in vitro diagnosis of impaired DNA mismatch repair system (MMR) affecting prognosis and selection of treatment in cancer patients. PlentiPlex™ MSI assays offer three different multiplexed MSI assays for the length analysis of five microsatellite loci. The mono- and dinucleotide panel recommended by the Bethesda guidelines and two Pentaplex mononucleotide panels, enabling evaluation of MMR status on DNA sequencer instruments. Microsatellites are genetic motifs consisting of short (one to six bases)...

Assist diagnosis of lymphomas PlentiPlex™ MYD88 L265P assay is intended for in vitro diagnosis of the leucine to proline mutation in codon 265 of the Myeloid differentiation primary response 88 protein (MYD88 L265P) in genomic DNA (gDNA) samples. The obtained results of the PlentiPlex™ MYD88 L265P assay are intended for assisting in the discrimination between patients with Lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia (LPL/WM) and nonHodgkin lymphoma. PlentiPlex™ MYD88 has a limit of detection of 0.25% PlentiPlex™ MYD88 L265P assay combines high sensitivity with ease-of-use and is...