Thermal Analysis Author Justin Lang Ph.D. PerkinElmer, Inc. 710 Bridgeport Avenue Shelton, CT 06484 Differential Scanning Calorimetry Performance Comparison Differential scanning calorimetry (DSC) is a commonly used technique for studying polymeric, pharmaceutical, and energetic materials. When considering which type of DSC to use to perform a specified measurement one typically chooses either a Power Compensation, or Heat Flux design. These instruments are often referred to as double and single furnace DSC respectively. PerkinElmer is the only vendor to provide both designs to customers, because we believe that both technologies provide unique advantages and users can choose the best type of DSC to meet their specific need. One of the more common questions is how do the instruments data compare when performing a standard measurement? To answer this question, a standard polystyrene (PS) and lowdensity polyethylene (PE) sample are tested using the conventional heat-cool-reheat method. DSC 8000/8500 • PerkinElmer’s new flagship DSC 8000 and DSC 8500 was developed for the user’s need for greater sensitivity and accuracy. They can be used for many applications including QA/QC applications, studying processes in plastics and pharmaceuticals. • The DSC 8000 provides outstanding sensitivity and reproducibility. It features PerkinElmer’s proprietary double-furnace technology, which directly measures the heat flow between two independent furnaces. It provides the most precise energy measurements over the whole temperature range of any DSC in order to meet the most demanding applications. There is an optional 96-position autosampler available and the DSC 8000 can be upgraded to a DSC 8500. • The DSC 8500, while providing all of the features of the DSC 8000, also offers HyperDSC® heating and cooling with extremely fast controlled scanning rates and in-situ ballistic cooling important for applications such as isothermal crystallization, polymorph/amorphous-material studies and high sensitivity mea

• PerkinElmer’s new compact, single furnace DSCs, the DSC 4000 and 6000, provide a solution for a wide range of routine applications in the academic, polymer and pharmaceutical markets. • Heat from 25-150 ˚C @10 ˚C/min • The DSC 4000 is upgradeable to the DSC 6000 and has the option of a 45-position autosampler. The DSC 6000 gives you all of the advantages of the DSC 4000 but also includes Modulated Temperature DSC (MT-DSC) technology for easier data interpretation and additional capabilities for product development and troubleshooting. • Hold for 2 min @ 150 ˚C • Cool at 50 ˚C/min to 25 ˚C •...

PerkinElmer, Inc. 940 Winter Street Waltham, MA 02451 USA P: (800) 762-4000 or (+1) 203-925-4602 www.perkinelmer.com l>PerkinElmer' For a complete listing of our global offices, visit www.perkinelmer.com/ContactUs Copyright ©2010, PerkinElmer, Inc. All rights reserved. PerkinElmer® is a registered trademark of PerkinElmer, Inc. All other trademarks are the property of their respective owners.