
Group: PHC Corporation
Catalog excerpts

THE SEPSIS MARKER PATHFAST PRESEPSIN TM » Whole blood » Early prognosis » Risk stratification » Patient monitorin
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What is PATHFAST TM Presepsin? PATHFASTTM Presepsin is a chemiluminescent enzyme immunoassay (CLEIA) for the quantitative measurement of the Presepsin concentration in whole blood or plasma. PATHFASTTM Presepsin improves the diagnosis and prognosis of sepsis defining its level of severity. It is a valid indicator of risk stratification in septic patients. Due to the fast analysis within 15 minutes and the high prognostic value even at patient’s admission, PATHFASTTM Presepsin is useful in laboratories, emergency- and intensive care units and neonatal departments. An early diagnosis with an...
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The diagnostic validity of Presepsin has been evaluated in numerous clinical studies. Comparisons of different medical scores and relevant biomarkers in sepsis diagnosis revealed an important role for PATHFASTTM Presepsin. Improved 30 day mortality prediction (Fig. 3) Presepsin showed superior risk of 30 day mortality prediction at admission in septic patients compared to APACHE II, GCS, MEDS, SOFA and procalcitonin. Fig. 4A: ROC curves for 30 day mortality at admission for Presepsin, PCT, SOFA, and qSOFA alone Fig. 4B: ROC curves for 30 day mortality at admission for Presepsin, and Lactate...
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Fig. 6: Decision thresholds of PSEP for early risk stratification in patients with sepsis Presepsin (pg/ml) Negative Predictive Value and cut off values (Fig. 6) Systemic infection not probable An important diagnostic factor is the high Negative Predictive Value (NPV) of Presepsin. In fact for healthy individuals, not affected by a clear bacterial outbreak, the values of Presepsin are below 200 pg/mL. A Presepsin cut off value of 1.622pg/ml excludes 30 day mortality by a Negative Predictive Value (NPV) of 98,5% (3). Presepsin concentration is already related to the severity of the disease...
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PATHFAST TM Test Principle PATHFAST TM Technical Specifications Instrument type Throughput Measuring time Sampling material Measuring principle Reaction temperature Sample volume Data storage Datatransfer Weight El. requirements Power consumption Monitor/keyboard Printer PC Interface Calibration 24-h operation (stand-by) Desktop Immunoassay Analyzer Up to 6 samples or parameters per run <17 minutes for 6 samples using emergency markers or PATHFASTTM Presepsin Whole blood, plasma, serum Chemiluminescence enzyme immunoassay technology (CLEIA) and Magtration® technology. 37 °C 100 µl Patient...
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Product List PATHFAST TM for critical care and sepsis diagnostics Item number Pack size PATHFAST TM pipette tips PATHFAST TM B.R. A.H.M.S PCT control set PATHFAST TM Presepsin control set SYSTEM PATHFAST TM Immunoanalyser Analyzer for the detection of cardiac and other emergency parameters and sepsis CONSUMABLES AND ACCESSORIES REAGENT KITS FOR CRITICAL CARE DIAGNOSTICS PHC Europe B.V. Nijverheidsweg 120, 4879 AZ Etten-Leur, The Netherlands Phone: + 31 76 543 38 33 email: marketing@eu.phchd.com REAGENT KITS FOR SEPSIS DIAGNOSTICS
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