VH® IVUS Clinical Applications
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Catalog excerpts

VH® IVUS Clinical Applications - 1

VH IVUS ® The Gold Standard for Complete Lesion Assessment Lesion Risk Assessment Longitudinal Stent Placement Transplant Patient Monitoring Distal Protection Carotid Stenting Research Necrotic Core Dense Calcium Fibrous Fibro-Fatty Volcano’s VH IVUS technology uses advanced, proprietary spectral analysis techniques to classify plaque into 4 tissue types with 93-97% accuracy.1 Based on 10 years of research with over 200 scientific publications in peer-reviewed journals, the technology allows for simplified image interpretation and a complete view into the severity of a patient’s disease. 1 Nair A et al. Automated coronary plaque characterisation with intravascular ultrasound backscatter: ex vivo validation. EuroInterv 2007; 3:113-120.

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VH® IVUS Clinical Applications - 2

Clinical Applications for Today Lesion Risk and Assessment of Disease Severity Non-Culprit Lesions Results of the landmark PROSPECT trial2 of 700 ACS patients indicate that VH IVUS changes the risk profile of non-culprit, angiographically intermediate lesions. • VH-TCFA lesions were predictive of events. PIT lesions were protective with a 0.2% event rate per year at 3 years suggesting safety of deferral. • Lesions with VH-TCFA, MLA<4mm2, and plaque burden >70% exhibited 18.2% MACE at 3.4 years. • VH IVUS can improve the accuracy of IVUS–based assessments of lesion VH-TCFA, “predictive” of...

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VH® IVUS Clinical Applications - 3

VH IVUS ® The Gold Standard for Complete Lesion Assessment Distal Protection • For STEMI patients, distal embolization during PCI is a complicating factor associated with poor prognosis and increased rate of acute procedural complications. • Higher necrotic core volume is predictive of ST-segment re-elevation associated with distal embolization.5 VH IVUS observations may influence the decision to use embolic protection devices or other therapeutic options. Carotid Stenting 5 Kawaguchi et al. Usefulness of Virtual Histology Intravascular Ultrasound to Predict Distal Embolization for...

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VH® IVUS Clinical Applications - 4

VH IVUS ® The Gold Standard for Complete Lesion Assessment Beyond the clinical applications of today, VH IVUS supports the advances of tomorrow. • Fully validated, with over 200 scientific publications in peer-reviewed journals, more than any other plaque composition technology. • Used in multiple clinical studies including IBIS II, BLAST, ADAPT, and the landmark PROSPECT study of 700 ACS patients published in the New England Journal of Medicine. • The only FDA-approved tissue classification technology with proven prospective clinical outcome data. Research Areas Disease progression and...

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