List of PhysioFlow clinical studies
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NEW STUDIES Category Lung disease and Internal medicine Title • Greater exercise tolerance in COPD during acute intermittent compared to continuous shuttle walking protocols: A proof-of-concept study • Repeated cardiopulmonary performance measurements in young competitive handball players with and without SARS-CoV-2 infection • Haemodynamic compensations for exercise tissue oxygenation in early stages of COPD: an integrated cardiorespiratory assessment study • Cardiac output and arteriovenous oxygen difference contribute to lower peak oxygen uptake in patients with fibromyalgia •...

INTRODUCTION This document is a list of abstracts of the studies that have been published involving the PhysioFlow technology. Some of them are abstracts of full papers published in peer reviewed journals and some are abstracts of presentations at conventions. They are categorized following the intent of the study (validation, application, or pure research) and also following applications (critical care, cardiology, physiology, etc.). They represent the start of the art about PhysioFlow, to the best of our knowledge. Some of these studies are quite old and reflect the performance of the...

1. Validations 1.1 Fick Principle/Exercise 1.1 FICK PRINCIPLE/EXERCISE A New Impedance Cardiograph Device for the Non-invasive Evaluation of Cardiac Output at Rest and During Exercise: Comparison with the "Direct" Fick Method Abstract, European Journal of Applied Physiology, Volume 82 Issue 4 (2000) pp 313-320 Authors: • Anne Charloux, • Evelyne Lonsdorfer-Wolf, • Ruddy Richard, • Eliane Lampert, • Monique Oswald-Mammosser, • Bertrand Mettauer, • Bernard Geny, • Jean Lonsdorfer. Service des Explorations Fonctionnelles Respiratoires, Cardio-Circulatoires et de l'Exercice, Hôpitaux...

1. Validations 1.1 Fick Principle/Exercise Non-invasive Cardiac Output Evaluation during a Maximal Progressive Exercise Test, Using a New Impedance Cardiograph Device European Journal of Applied Physiology, Volume 85 Issue 3/4 (July 2001) pp 202-207 DOI 10.1007/s004210100458 Authors: • Anne Charloux, • Evelyne Lonsdorfer-Wolf, • Ruddy Richard, • Eliane Lampert, • Monique Oswald-Mammosser, • Bertrand Mettauer, • Bernard Geny, • Jean Lonsdorfer, • Stéphane Doutreleau, • Martin Buchheit. Service des Explorations Fonctionnelles Respiratoires, Cardio-Circulatoires et de l'Exercice, Hôpitaux...

1. Validations 1.1 Fick Principle/Exercise Measurements of Cardiac Output during Constant Exercises: Comparison of Two Non-Invasive Techniques Int J Sports Med 2004; 25: 145-149 DOI: 10.1055/s-2004-819949 Laboratoire de Physiologie Médecine, Place St Jacques, Besançon, France 2 Laboratoire des Sciences du Sport, Place St Jacques, Besançon, France 3 University of Waterloo, Department of Kinesiology, Waterloo, On, Canada 1 Abstract: We compared cardiac output (CO) determined simultaneously by electrical impedance cardiography method (COICG) and by the CO2 rebreathing technique (CO2REB) during...

1. Validations 1.1 Fick Principle/Exercise Does Thoracic Bioimpedance Accurately Determine Cardiac Output in COPD patients during Maximal or Intermittent Exercise? Chest. 2005 Apr;127(4):1122-31. Authors: • Bougault V, • Lonsdorfer-Wolf E, • Charloux A, • Richard R, • Geny B, • Oswald-Mammosser M. Service des Explorations Fonctionnelles Respiratoires et de l'Exercice, Hopital Civil, BP 426, 67091 Strasbourg Cedex, France Study objectives: The monitoring of cardiac output (CO) during exercise rehabilitation in patients with COPD, often including strenuous exercise, is advisable. Invasive...

1. Validations 1.1 Fick Principle/Exercise Reliability of Peak VO(2) and Maximal Cardiac Output Assessed using Thoracic Bioimpedance in Children Eur J Appl Physio,. 2005 Jun; 94(3):228-34. Epub 2005 May 26. Authors: • Welsman J, • Bywater K, • Farr C, • Welford D, • Armstrong N. Children's Health and Exercise Research Centre, University of Exeter, Heavitree Road, Exeter, EX1 2LU, UK. j.r.welsman@ex.ac.uk Abstract: The purpose of this study was to evaluate the reliability of a thoracic electrical bioimpedance based device (PhysioFlow) for the determination of cardiac output and stroke volume...

1. Validations 1.1 Fick Principle/Exercise Does Advanced Cardiac Impedance Technology Accurately Measure Cardiac Output During Submaximal Steady State Exercise? Control/Tracking Number: 09-SA-3991-ACSM Activity: Scientific Abstract Current Date/Time: 11/3/2008 8:13:33 PM Authors: • Craig E. Broeder, • FACSM, • Jarod Hickock, • Amanda Burditt Benedictine University, Lisle, IL. Email: jazzercb@mac.com This study determined if advanced cardiac impedance technology (ACI) could accurately measure cardiac output during steady-state cycling exercise compared to values calculated using the direct...

1. Validations 1.1 Fick Principle/Exercise The Ergogenic Effect of Recombinant Human Erythropoietin on VO2max Depends on the Severity of Arterial Hypoxemia Citation: • Robach P, • Calbet JAL, • Thomsen JJ, • Boushel R, • Mollard P, • et al. (2008) The Ergogenic Effect of Recombinant Human Erythropoietin on V ˙ O2max Depends on the Severity of Arterial Hypoxemia. PLoS ONE 3(8): e2996. doi:10.1371/journal.pone.0002996 Editor: Timothy Secomb, University of Arizona, United States of America Funding: This study was supported by research fundings from Anti Doping Danmark (Denmark),...

1. Validations 1.1 Fick Principle/Exercise measurement: Agreement between impedance and dye dilution for cardiac output This graph shows the agreement (Bland-Altman plot) between the cardiac impedance technique and the indocyanine green dye dilution method for measuring cardiac output during exercise obtained from 55 measurements in seven subjects. For each measurement, the difference between the two methods is plotted against the average of both techniques. The solid line indicates the mean bias, while the dotted lines indicate the 95% confidence intervals (2×standard deviation).