TriPollar OxyGeneo & TECHNOLOGIES
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TriPollar OxyGeneo & TECHNOLOGIES - 1

TriPollar & OxyGeneo TECHNOLOGIES EXPECT MORE A Novel Skin Care Platform OxyGeneo And TriPollar RF Technologies AlexLevenberg, M.D. - Physician's Center UriShpolansky, Ph.D. - Physiological Models

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TriPollar OxyGeneo & TECHNOLOGIES - 3

Introduction: Aesthetic skin treatments are a common practice among women and men throughout the globe, crossing borders of culture and socio-economic status. Facials or skin treatments of various body areas have been popular throughout the ages and have been documented as early as ancient Egypt and Greece. A variety of treatments are available for exfoliation and infusion of skin enhancement products and there is a growing demand for skin oxygenation treatments. The innovative geneO+™ Skin Care Platform enables a variety of skin enhancement treatments for a wide range of skin...

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TriPollar OxyGeneo & TECHNOLOGIES - 4

Hence, a decrease in blood pH or an increase in CO2 levels will induce a release of oxygen from the hemoglobin proteins and a decrease in carbon dioxide levels. In addition to the OxyGeneo, the geneO+ platform offers an add-on applicator emitting TriPollar RF, the 3rd generation RF technology which has been well validated through numerous peer-reviewed published papers. RF is a well established technology used for dermal heating and stimulation of collagen formation (6,7). The TriPollar technology uses three or more electrodes designed to deliver RF current into the skin, inducing a focused...

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TriPollar OxyGeneo & TECHNOLOGIES - 5

Combination of OxyGeneo & TriPollar technologies The TriPollar RF add-on applicator of the geneO+ platform, based on the well-established TriPollar technology, utilizes four electrodes to deliver RF energy into the skin to generate heat through resistance in the dermal layer. Heating the dermis stimulates dermal activity, tightens collagen fibers and increases new collagen production. The geneO+ TriPollar RF applicator has three preset power levels: Low, Medium and High which differ in term of temperature range and RF intensity. The operator can custom tailor the treatment specifications...

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TriPollar OxyGeneo & TECHNOLOGIES - 6

TriPollar & OxyGeneo EXPECT MORE Effect of OxyGeneo treatment on tissue gasses Figure 2: The graph demonstrates a return of CO2 levels to baseline values 15minutes after treatment while the O2 levels rise above baseline levels. [The values presented as average ± S.EJ. Effect of OxyGeneo treatment on blood perfusion Figure 3: Skin blood perfusion increases immediately after the treatment and gradually returns to base line levels. 15 min after treatment the values are higher than the baseline. The values are presented as average percent OxyGeneo clinical results and subject satisfaction...

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TriPollar OxyGeneo & TECHNOLOGIES - 7

TriPollar & OxyGeneo TECHNOLOGIES EXPECT MORE Subject Satisfaction First Treatment Last Treatment Figure 6: Subject satisfaction graph of variable skin conditions following first and last OxyGeneo treatment. Results demonstrate a rated improvement in subject satisfaction of variable skin conditions. An obvious trend of improvement is noticed between first and last treatment in all evaluated parameters. OxyGeneo and TriPollar combination Figures 7-9 demonstrate immediate and long term results of combination treatments using OxyGene and TriPollar technologies. Results demonstrate the...

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TriPollar OxyGeneo & TECHNOLOGIES - 8

TriPollar & OxyGeneo EXPECT MORE When massaging skin tissue the effect is usually an increase in blood perfusion and a decrease in transcutaneous CO2 (TCpCCh) due to higher evacuation rate and increase in transcutaneous O2 (TCpCh) due to increase in oxygenated blood supply. Usually this process is accompanied by an increase of skin temperature. However, Pollogen's OxyGeneo treatment resulted in an increase of about 12% in TCpC02 m mediately after the treatment with concomitant increase in blood flow and lowered skin temperature. Furthermore, 15 minutes after the treatment, the TCpCb level...

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TriPollar OxyGeneo & TECHNOLOGIES - 9

Figure 12: Illustration of the infusion process and skin oxygenation during a OxyGeneo treatment. The positive effects of OxyGeneo treatment was noticed by all subjects participating in the clinical evaluation. The positive subject feedback confirms the study results of increased oxygenation and enhanced infusion of therapeutic gels. The unique combination of light peeling of the skin’s outer layer with oxygenation and infusion of beneficial skin enriching components, enable an efficient time saving treatment with remarkable visible immediate results. The combination of OxyGeneo with the...

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TriPollar OxyGeneo & TECHNOLOGIES - 10

1. Savin E, Martineaud JP: Vasomotor Effects o 2f Traniscutanenous CO Stage II Peripheral Occlusive Arterial Disease, Angiology. Journal of Vascular Disease. (Sep 1995); Vol 46 775-9 2. Schmidt KL: Carbon Dioxide Bath (Carbon Dioxide Spring). White paper (Center for Clinical Research in Rheumatology, Physical Medicine and Balneotherapy Bad Nauheim, Germany) 3. Hartmann B, Drews B: CO2 Balneotherapy for Arterial Occlusion Diseases: Physiology and Clinical Practice. White paper. Institute of Applied Physiology and Balneology, University of Freidburg 4. Jensen FB: Red blood cell pH, the Bohr...

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