M I C R O L U T E ™ S A M P L E P R E PA R AT I O N RANGE BROC HURE

Porvair Sciences introduces Microlute™, the innovative range of sample preparation products designed and manufactured to deliver uncompromised chromatographic performance with a whole new level of reliability and reproducibility. With over 30 years’ experience in manufacturing porous plastics and microplates for chromatography applications, these unique capabilities have led to the development of the Microlute™ hybrid technology, a solid active filter that is set to redefine the standards of sample preparation workflows. At Porvair Sciences we recognise the importance of time, quality and cleanliness...

Microlute™ Hybrid Technology Porvair Sciences expertise in porous plastics manufacturing has led to the development a unique composite filter, a porous plastic structure containing chromatographic active media immobilised within evenly distributed pores. This hybrid technology is designed to offer greater control over flow rates throughout sample preparation methods. Consistent flow of liquids through the active media maximises removal of contaminants and recovery of analytes with greater reproducibility. The Microlute™ hybrid technology enhances the sensitivity and integrity of analytical methods...

Microlute™ PLR Phospholipids are a ubiquitous class of amphiphilic molecules found in all living organisms as a major component of cell membranes. Although essential to cells, removal of phospholipids from biological samples is a fundamental sample preparation step to eliminate a major source of ion suppression and obtain true analyte signals for analysis. Utilising the strengths of the hybrid technology, Microlute™ PLR effectively removes all classes of phospholipids and maximises analyte recovery with market-leading reproducibility. Market Leading Reproducibility < 4 % RSD for Higher Confidence...

Microlute™ CP takes SPE to a new level of performance by enhancing the reproducibility of analyte extraction and recovery from biological, environmental and chemical samples. Unlike traditional loose-filled SPE methods, Microlute™ CP uses a hybrid structure, a solid interconnected network of evenly distributed pores combined with the retentive media. This design enhances the flow-through of samples to maximise interactions between analytes and the solid phase to deliver a reproducible SPE method that excels in performance, cleanliness and sensitivity. Phases: Reversed Phase (RP), Strong Cation...

Microlute™ CP reversed phase (RP) plates and cartridges contain immobilised polymeric DVB (divinyl-benzene) within its structure for retention of neutral and non-ionisable compounds. The stationary phase allows analytes to be retained via hydrophobic interactions and polar contaminants are simply removed by washing with a polar solvent such as water. Depending on the desired analysis, retained analytes can be gradually eluted off in fractions with increasingly non-polar solvents or flushed all together from the phase with a strong organic wash. Microlute™ is an ideal starting point for many applications...

Ion exchange cartridges and plates retain, and separate analytes based on their charge or its ionisation behaviour with respect to pH or ionic buffer strength. The Microlute CP ion exchange range covers both anion and cation in both weak and strong forms to cover the full range of sample and analyte types. All forms use the innovative Microlute CP hybrid technology to offer the highest available reproducibility levels available, without compromising the chromatography. Sample matrix: Low ionic strength aqueous sample matrix Cationic exchange: Positively charged with ionisable analytes Anion exchange:...

Easily extract a wide range of acidic, basic and neutral analytes from a range of biological or aqueous samples with a superior method of liquid extraction, supported liquid extraction (SLE). Microlute™ SLE 96 well plates and cartridges use selectively sourced diatomaceous earth (DE) as the solid support to maximise absorption of the aqueous solutions to allow simpler recovery of analytes from samples with greater reproducibility. Analysis: UHPLC, HPLC, GC, LCMS, GCMS Applications: Forensics, pharmaceutical, drug discovery and clinical Formats: 96 well plates and cartridges Weight: Max Load Volume...

The Microlute™ Protein Precipitation Plate (PPP) is designed to efficiently precipitate proteins from plasma and serum. Using the crash method, proteins are precipitated or ‘crashed’ out with acetonitrile and filtered. The 96 well plate efficiently handles processing up to 96 samples at once and ensure minimal protein contamination during injection into chromatographic systems. Analysis: UHPLC, HPLC, GC, LCMS, GCMS Formats: 96 well plates The Microlute™ PPP plate uses a novel dual filter to efficiently removal proteins without leakage of samples. The super hydrophobic filter prevents samples...

Vacuum manifolds are used to draw liquid through a filter or SPE plate into either a waste tray or a collection plate. The application of vacuum increases the speed at which samples can be collected. The Microlute™ vacuum manifold from Porvair Sciences is precision machined from crystal clear acrylic (top plate) and acetal polymer (plenum chamber). The acrylic top plate allows visual access to the plenum chamber for checking progress of the separation process. • Designed to take most filter plates manufactured to the SBS/ANSI specification with long drip directors • Also designed so that SPE...

Glass vials are essential to any chromatography workflow. We offer a wide range of vials, seals, inserts and caps to suit routine and high throughput sample analyses. Designed and manufactured by JG Finneran, all vials are compatible with robotic arm autosamplers. R.A.M. vials are designed specifically to work with robotic arm autosamplers that have a crimp style height with the convenience of a screw thread configuration. Choose from clear or amber Type I borosilicate glass. 12 x 32 mm 9 mm threads, borosilicate glass. Product Number Big Mouth Inserts ig mouth limited volume inserts are designed...