Filter Dryers
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ANFD Agitated Nutsche Filter Dryers

ANFD – Agitated Nutsche Filter Dryers Agitated Nutsche Filter Dryers Every day, PSL Agitated Nutsche Filter Dryers (ANFD) are assisting pilot and production facilities around the world to reliably manufacture and bring their products to the market faster. Our technology is being used in commercial production in a wide range of industries including pharmaceuticals and fine chemicals, for sensitive and/or high value products. PSL’s full size Agitated Nutsche Filter Dryers isolate and wash solids in the most complex chemical and pharmaceutical synthesis processes and challenging production...

ANFD – Agitated Nutsche Filter Dryers PSL’s Agitated Nutsche Filter Dryer 1 - Top Driven Central Agitator Low speeds High torque 2 - Double Mechanical Seal Hygienic design CIP and SIP suitable 3 - Pressure Envelope Operates under pressure (filtration) Operates under vacuum (drying) 4 - Heating Zones Base, vessel jacket and agitator 5 - Agitator Height Adjustment Hydraulic raise/lower cylinders Compact hydraulic pack 6 - Filtering Element Metallic sintered mesh Filtering cloth Interchangeable design 7 - Discharge Plug Manual or automated Compatible with containment devices

ANFD – Agitated Nutsche Filter Dryers Combined Filtration and Drying PSL’s versatile ANFD solutions combine all the processing steps within a single piece of equipment. Firstly, solid-liquid separation is carried out, also known as filtration. The next step often consists of washing the product to remove impurities and/or solvent traces. The final steps are to dry and collect the solids. In the majority of cases the solid is the product of interest but filter dryer technology can also be used in processes where the filtrate (liquid) is the desired product. It is also possible to retain both...

ANFD – Agitated Nutsche Filter Dryers ANFD Processing Agitator cGMP, single piece design Heating capability on larger sizes Straight tapered blades, with underside blades for added differential mixing Side fins at extremities to prevent sidewall build-up Double mechanical seal design, suited for use with HPAPI or sterile applications Metallic bellows for vessel pressure seal. Flat Base Design Minimum liquid “dead volume” under the filter mesh (drainage channels), to reduce solvent waste Flat base design with jacket allows for direct heat transfer to product due to the energy efficient...

ANFD – Agitated Nutsche Filter Dryers Base Automation Capability Economical pressure C-clamp design. Manually operated. Automatic hydraulic raise/lower with manual clamp/unclamp Fully automatic bayonet base (hydraulic raise/ lower and hydraulic lock/unlock) Dust Filter Protection of vacuum lines via filtering cartridge (metallic sintered mesh or cloth) Nitrogen pulse back feature to unclog the filtering elements if required Integral design to minimise headspace required on vessel top dome, including safe change feature Cleaning PSL filter dryers incorporate an internal CIP ring with PTFE...

ANFD – Agitated Nutsche Filter Dryers Software Automation PSL’s ANFD range is available as stand-alone equipment for client/third-party integration or in combination with a PSL software and automation package. Different levels of control/automation can be supplied to add speed and flexibility to manufacturing processes: Field instrumentation, wired to local junction boxes for client to integrate to their DCS (Distributed Control System) Basic PLC, HMI and software package for controlling ANFD with process exchange signals to client DCS Additional agitator sequence recipes; 10 steps for...

ANFD – Agitated Nutsche Filter Dryers Containment Many industrial filtration and drying processes require the integration of containment technology to protect operators from highly toxic compounds and/or to protect sensitive products from a harmful production environment. Although the filtration and drying phases within an ANFD require no physical operator intervention, in certain circumstances unloading the product can remain manual. If the end product is potent/toxic or oxygen sensitive, as it is often the case within pharmaceutical applications with an Active Pharmaceutical Ingredient...

ANFD – Agitated Nutsche Filter Dryers ANFD Range *Other configurations available upon request.

ANFD – Agitated Nutsche Filter Dryers Successful Scale Up The GFD® Family is perfectly suited to complete scale-up and scale-down studies as it helps maintain key objectives such as product quality, product yield and batch consistency, along with the key production parameters of filtration time, washing time and drying time etc. The GFD® product range is designed to streamline scale-up development from early R&D activities (GFD®Lab) and GLP batches up to Pilot Plant production (GFD®Pilot). R&D and Pilot Filter Dryers Evolutive sizes for filtration area: • GFD®Lab with 0.002m² and 0.01m²...

Taking your process further, together. For over 35 years, Powder Systems Limited (PSL) has been at the forefront of designing and engineering advanced technology to support process development. We are a globally recognised, award-winning business with expertise in pharmaceutical and chemical processing. Our focus is to help clients and partners address challenging manufacturing processes by providing fit-for-purpose solutions from our wide range of Microsphere Processing, Filtration and Drying ranges. w: powdersystems.com e: info@powdersystems.com t: +44 (0) 151 448 7700 Quality •...