GFD® Pilot
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GFD®Pilot Pilot Plant Agitated Nutsche Filter Dryer

GFD® - Pilot Plant Nutsche Filter Dryer Technology GFD®Pilot The GFD®Pilot is an Agitated Nutsche Filter Dryer (ANFD) that carries out solid-liquid separation processes at kilolab and pilot scale. It facilitates feasibility and proof of concept activities developed during smaller scale research and development stages. In spite of being a smaller, compact filter dryer, it provides the quality, reliability and efficiency of the full size PSL ANFD filter dryers. PSL’s unique GFD® technology was developed to overcome the well-known production challenges faced by manufacturers when using...

GFD® - Pilot Plant Nutsche Filter Dryer Technology GFD®Pilot at a Glance 1 - Agitator System Height-adjustable system with manual operation Bidirectional motor (electrical or pneumatic) for smoothing and ploughing of filter cake 5-25 rpm with up to 68 N•m torque Aids uniform drying of filter cake 2 - Vessel Manufactured from Borosilicate 3.3 glass, 316L Stainless Steel or Alloy 22 Integrated heating jacket aids quick and effective drying of the product Easy to clean High chemical and heat resistance Ergonomic vessel open/close and support via frame brackets Process nozzles: Drain/Filtrate,...

GFD® - Pilot Plant Nutsche Filter Dryer Technology Combined Filtration and Drying Agitated Nutsche Filter Dryers separate solids from liquid in batchoriented processing. The product of interest is usually the solid but in some cases the filtrate liquid or both, thus the need for versatile and flexible equipment that can adapt to achieve the desired outcome. The GFD®Pilot is an all-in-one filter dryer designed for use at pilot plant production scale. It complies with Good Laboratory Practices (GLP) and is commonly used for pharmaceutical and fine chemical processing applications. Developers...

GFD® - Pilot Plant Nutsche Filter Dryer Technology Maximum Product Recovery Maximising yield is crucial at pilot scale feasibility stages and/or small-scale production. The GFD®Pilot is designed with this in mind, given the importance of the final product. Following process completion, the product batch is collected with ease due to the design of the filtration basket which can be removed completely from the GFD® vessel. The GFD® basket is suitable for multi-product applications as it facilitates quick and easy changeover of filtration meshes with various pore-sizes and materials such as...

GFD® - Pilot Plant Nutsche Filter Dryer Technology Flexible Modular Design The compact, mobile GFD®Pilot filter dryer provides production flexibility due to its modular design. As with the GFD®Lab range, the base frame is compatible with all relevant vessel materials (Borosilicate 3.3 Glass, 316L Stainless Steel and Alloy 22), offering a simple, fit-for-purpose solution. The motor options — electrical or pneumatic depending on the environment of use — are also compatible with the frame drive mount. The frame has been designed as compact as possible to allow integration within fume cupboards...

GFD® - Pilot Plant Nutsche Filter Dryer Technology Hazardous Area Compliant When scaling up to the operational volumes available with the GFD®Pilot, the use of organic solvents in chemical and pharmaceutical processes often means hazardous area considerations must be taken into account. To overcome this, PSL offers alternative agitator drives suitable for such environments with appropriate certification, for example ATEX and NFPA. Additionally, the use of pneumatic motor drives ensures the design is kept compact. Pressure Directives When higher operating pressures are required, metallic...

GFD® - Pilot Plant Nutsche Filter Dryer Technology Containment-Ready As one of the early pioneers of containment technology, PSL developed the unique GFD®FilterBox isolator range to accommodate all the types of vessel used with the GFD®Pilot. By opting for a GFD®FilterBox operators are safe-guarded from the most toxic/potent compounds and the product is protected from production environments. PSL can also provide integration packages with/for third-party containment providers. Please contact PSL for further details.

GFD® - Pilot Plant Nutsche Filter Dryer Technology Predictive Scalability The GFD®Pilot is perfectly suited as the intermediate step between laboratory studies and commercial manufacturing as it helps maintain key objectives such as product quality, product yield and batch consistency, along with the key production parameters of filtration time, washing time and drying time etc. The GFD® product range is designed to streamline scale-up development from early R&D activities and GLP batches up to Pilot Plant production. For Commercial-Scale production, PSL also offer a range of cGMP compliant...

GFD® - Pilot Plant Nutsche Filter Dryer Technology Commercial Filter Dryers 0.05m2 up to 1.00m2 Filtration area Full cGMP design: Double Mechanical Seal, Agitator Bellows, Integral Dust Filter, CIP Ring, etc. Filtration Mesh versatility with cloth or metallic sintered mesh use within a single design. Fully compliant for Hazardous Area (ATEX/NFPA) Contained product off-loading options available for operator protection on API/HPAPI Applications Full Automation Capability available to industry standards (GAMP5, 21 CFR Part 11, etc.)

Taking your process further, together. For over 30 years, Powder Systems Limited (PSL) has been at the forefront of designing and engineering advanced technology to support process development. We are a globally recognised, award-winning business with expertise in pharmaceutical and chemical processing. Our focus is to help clients and partners address challenging manufacturing processes by providing fit-for-purpose solutions from our wide range of Microsphere Processing, Filtration and Drying ranges. w: powdersystems.com e: info@powdersystems.com t: +44 (0) 151 448 7700 Quality •...