1 Sensors for Medical Research & Life Sciences o Minimally invasive or even non-invasive measurements o Online monitoring of O2 & pH o CO2 monitoring available for selected applications o Imaging of analyte gradients o Customized OEM solutions

Sensors for Medical Research & Life Sciences Biomass Contact us and we find your customized solution!

Sensors for Medical Research & Life Sciences We bring to light what‘s inside... Products Made in Germany Company Profile PreSens offers a broad range of sensor systems for end users in Bioprocess Control, Biological & Environmental Research, the Food & Beverage industry as well as other industrial applications. Based on research activities started in the 1980‘s PreSens Precision Sensing GmbH was founded in 1997 as a spin-off from the University of Regensburg, Germany. We offer systems for Oxygen measurement in gases and liquids Non-invasive online pH, CO2 and oxygen measurement Oxygen and pH...

...and work for the following industries. Biotech & Pharma Research Our Biotech & Pharma business field helps pharmaceutical companies such as Roche and DSM to improve their bioprocess develQuality Control opment with PreSens sensors. With two decades of customer feedback our product development provides efficient solutions for your needs. Food & Beverage A cooperation with the market leader for beverage filling systems, Krones AG, Neutraubling, triggered our Food & Beverage business field in the late 1990‘s. PreSens supplies sensors for checking the oxygen-tightness of packaging and special...

Sensors for Medical Research & Life Sciences featured SENSORS & METERS Sensor Technology for O2, pH & CO2 Monitoring Our most recent business field arose from a cooperation with renowned medical technology manufacturers from the Medical Devices sector. PreSens supplies OEM parts, which are integrated into more complex medical systems or multisensory tools for high throughput analyses. Our microsensors, sensor spots, and imaging systems are already applied for high precision measurements in tissue engineering, microfluidics, and many other research fields in medical research and the life sciences....

Microx 4 trace + Needle-type Oxygen Microsensors (NTH-PSt7/8) The Needle-type Oxygen Microsensor can be inserted in engineered tissue or tissue samples and high resolution trace oxygen measurements can be performed. The sensor is connected to the portable Microx 4 trace oxygen meter for read-out. Single-use pH Flow-through Cell (FTC-SU-HP5) + EOM-pH-mini or Single-use O2 Flow-through Cell (FTC-SU-PSt3) + EOM-O2-mini Irradiated Single-use Flow-through Cells connected to the ElectroOptical Modules EOM-O2-mini and EOM-pH-mini can be integrated in customers’ systems for online perfusion monitoring....

Sensors for Medical Research & Life Sciences O2 Monitoring in Tissue Engineering & Regenerative Medicine One main issue in 3D engineered tissue is the development of oxygen and nutrient gradients towards the middle of an engineered tissue. With PreSens microsensors high resolution measurements inside the tissue can be performed. Our micromanipulator systems ensure exact localization of the measurement tip within a sample. With optical sensor foils integrated at the bottom of the tissue culture vessel 2D analyte maps can be recorded and gradient development can be followed over time. Gradients...

FEATURED SENSORS & METERS Tumor Research Recent research suggests that processes in the tumor microenvironment can influence its growth and development. In vivo experiments on tumor microenvironments are challenging and precise measurement devices are needed. PreSens microsensors with a tip size thinner than a hair combined with our micromanipulators allow to conduct most accurate on-the-spot measurements inside tissue. Even 2-dimensional assessment of analyte distributions over cross-sections of tumor tissue can be realized with the VisiSens™ imaging system. Minimally Invasive Brain Sensor PreSens...

Sensors for Medical Research & Life Sciences Sensor Solutions for Medical Research & Life Sciences Life Science Research Contact us and we find your customized solution!

PreSens offers customized sensor technology solutions. Right from the beginning PreSens can be your partner while finding new approaches: from specifica tions to implementation up to production of your tool. Don’t hesitate to ask for your individual solution: [email protected] SENSOR SOLUTIONS Patient Care SDR + SensorDishes® / SensorPlates oxygen and pH monitoring in multiwell and microtiter plates for screening and analysis purposes SFS Shake Flasks with Integrated Sensors + SFR vario online monitoring of shaken cultures CFS Cell Culture Flasks with Integrated Sensors + SFR monitoring...

Sensors for Medical Research & Life Sciences Featured Applications Perfusion Culture of Cell-seeded 3D Scaffolds for Tissue Engineering Since oxygen has a low solubility in culture medium it must be supplied to cells within 3D scaffolds via constant perfusion of the medium. The oxygen content before and after having passed by the cells can help to determine whether the flow rate applied is sufficient. PreSens flow-through cells with integrated optical sensors were incorporated in the construct at the inlet and outlet and allowed in-line measurement of oxygen tension. This way it was possible...

Monitoring O2 & pH Kinetics in 3D Culture of Disc-chondrocytes with the SDR SensorDish® Reader Hydrogel-based 3D culture systems offer particular advantages in regenerative medicine. The availability of oxygen within the culture medium and pH kinetics were analyzed with the SDR SensorDish® Reader. The measurement system enabled non-invasive detection of both culture parameters close to the cells inside 24-well dishes. The DO kinetics showed in detail how media changed and complex factors like cell proliferation influenced the O2 level inside the culture. pH kinetics also displayed characteristic...