High-performance, easy-to-use detection systems to simplify your research GbMax SYSTEMS

Ready for Your Research GloMax® Discover, Explorer and Navigator are state-of-the-art detection readers offering luminescence, fluorescence and absorbance detection capabilities with preloaded protocols and touch screen functionality. They make data analysis easy. Easy-To-Use The intuitive touchscreen display, preloaded protocols and automatic instrument gain adjustments make it simple to produce your data and analyze results. Integrated with Promega Assays Optimized, preloaded Promega protocols are part of the GloMax® Systems Software, minimizing the time you spend optimizing instrument settings,...

The Right Instrument for Your Needs GloMax® Discover, Explorer and Navigator offer a range of detection options. Purchase the instrument and modules you need now. Upgrade your system later as your laboratory needs change. GloMax® Systems Model Visible Absorbance UV-Visible Absorbance GloMax® Navigator Model GM2000/2010 GloMax® Explorer Model GM3510 GloMax® Explorer Model GM3500 GloMax® Discover Model GM3

Unpack, Plug In and Start Generating Data We’ve made it easy for you to quickly set up your GloMax® Detection System and begin collecting and analyzing data, right out of the box. Data Analysis No need to worry about manually adjusting the gain for luminescence reads. GloMax® Systems perform this adjustment for you, providing you with optimized settings. GloMax® Systems SMART Protocols provide additional data analysis options. Easily measure and analyze your results using the intuitive, preloaded software. GloMax® Systems software provides many of the required technical elements of a part 11...

Easy to Use for Your Application Automatic Filter Slides • Multiple reads without user intervention • Easily perform BRET and FRET studies • Customize filters for your needs Flexible Interface • Select a preloaded protocol or customize your own • Set up a plate map • View data in a heat map display to quickly identify trends • Easily export your results to a variety of locations including a local network, web-based cloud, LIMS or any drive desired Figure 2. Integrated Filter Slides for GloMax® Discover and Explorer. Figure 3. Heat Map Display.

Integrated with Promega Assays GloMax® Detection Systems offer superior performance for a wide array of assays for your research. The sensitivity, broad dynamic range and low well-to-well cross talk provide you with more usable and relevant data. Whether you study cell health, monitor cell viability or toxicity, or assay signaling pathways, GloMax® Systems produce data you can use. Are you developing drug candidates and monitoring kinase activity? These Detection Systems are ready to support your research. GloMax® Systems also detect readout from Promega bioassays and evaluate monoclonal antibody...

The Versatility and Performance You Need Easily read multiplexed cell viability, apoptosis and cytotoxicity assays. Efficiently read the output of kinase inhibitor screening and automatically analyze results. [digitonin], µg/ml Percent Activity Cytotoxicity (CellTox™ Green) Percent Vehicle Control (Viability) Screen Kinase Inhibitors Percent Vehicle Control (Cytotoxicity) Multiplex Assays Figure 6. Multiplexed cytotoxicity and viability assays performed on digitonin-treated K562 cells. Figure 7. Receptor tyrosine kinase inhibition was assessed following incubation with gefitinib, a selective...

Flexibility to Use Alone or as Part of an Automated Workflow The GloMax® Detection Systems can be used on a bench top or integrated into your automated workflow for higher throughput and walk-away operation. Automation Ready Third Party Integration GloMax Systems can be controlled by third-party scheduling software with liquid handling and plate stackers to give you complete, walk-away automation. The software is SiLA compatible, making integration device control simple as SiLA standards evolve. The GloMax® Systems can be integrated with Tecan Freedom EVO®, Hudson Robotics Solo™ and PlateCraneEX™,...

Luminescence • Low-noise PMT ensures collected light is not compromised • 10 to 1,000 times more sensitive than competitor instruments • No need to dilute samples or manage gain settings • 2 to 3 logs more usable data than competing instruments • Lower cross talk for more usable data Luminescence Module Specifications Detector Top-reading, head-on photon counting photomultiplier tube (PMT) Detection Limit 1.5 x 1021 moles of luciferase Linear Dynamic Range 9 logs Cross talk Less than 3 x IQ-5 (white, 96-well plate, Corning 3912) Injector System Specifications Number of injectors (optional) Two...

GloMax® Discover and Explorer System Specifications Luminescence • Low-noise PMT ensures collected light is not compromised • 10 to 1,000 times more sensitive than competitor instruments • No need to dilute samples or manage gain settings • 2 to 3 logs more usable data than competing instruments • Filtered luminescence readout for BRET or multi-wavelength distinction (for GloMax® Discover only) or total luminescence • Lower cross talk for more usable data • Five filters included for BRET and filtered luminescence assays such as NanoBRET®, Renilla/YFP BRET and Chroma-Glo™ (for GloMax® Discover...

Fluorescence • Uses powerful wavelength-matched, light-emitting diodes (LED) as excitation sources • LEDs closely match excitation profiles of commonly used fluorescent molecules to ensure high sensitivity • Reduces nonspecific light leakage, a common problem when using broad-spectrum light sources • Five excitation and emission filters included for common fluorescence assays; plus 1 customizable excitation and emission position • Or, customize two fluorescence excitation positions or all 6 emission positions to your needs Fluorescence Module Specifications Detector Light Source Read Position...