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F-Labo Fully-Automatic Capsule Filling Machine

F-Labo Fully-Automatic Capsule Filling Machine

F-Labo Fully-Automatic Capsule Filling Machine

Product catalog summary
Introduction
Qualicaps Co. offers high-quality hard gelatin, PEG, and HPMC capsules, along with a high-speed fully-automatic capsule filling machine, the F-series, designed for laboratory use in drug formulation and investigational drug manufacturing. This machine is renowned for its ability to fill various dosage forms and multilayer formulations, ensuring high precision even with minimal raw materials.

Key Features
  • Versatile Filling Capabilities: The machine can handle powders, granules, oils, pasty liquids, tablets, and combined formulations of incompatible drugs.
  • Easy Cleaning and Size Exchange: All drug contact parts can be easily cleaned and overhauled, enhancing cleaning validation results.
  • High-Precision Filling: The machine divides filling into 12 sections with intermittent driving, allowing for easy speed adjustments.

Technical Specifications
  • Dimensions: 775 mm wide × 685 mm deep × 1,740 mm high (excluding the hopper)
  • Footprint: 5.5 m²
  • Weight: 770 kg
  • Production Capacity: 1,000 to 2,600 capsules per hour
  • Target Capsule Sizes: 000, 00, 0, 1, 2, 3, 4, 5
  • Utilities: Power source 2φphase, AC200 to 220 V, 50/60 Hz, 2.0 KVA; Vacuum and compressed air requirements specified.

Operational Procedures
  • Rectification and Transportation: Patented in 10 countries, the rectifier ensures precise division and easy assembly.
  • Capsule Separation: Utilizes a vacuum shoe with an O-ring to prevent capsule damage during separation.
  • Drug Substance Filling: Capable of filling a wide range of drug forms, with temperature and discharge rate control.
  • Powder and Granule Filling: Employs die-compress and 2-layer filling methods for precise weight control and multi-layer granule filling.
  • Tablet Filling: Can fill capsules with multiple mini tablets or combinations of fast and slow-dissolving tablets.
  • Filling Unit Replacement: The unit can be easily removed for size changes or cleaning.
  • Joining: Ensures precise cap-to-body connection using advanced technology to prevent failures.

Related Facilities
  • S-15 capsule sealing machine
  • AWC-L automatic weight controller
  • CWI-40 capsule/tablet weight inspection machine
  • CES-50 capsule inspection machine

Contact Information
Qualicaps Co., Ltd., 321-5 Ikezawacho, Yamatokoriyama, Nara, 639-1032, Japan. Phone: 81-743-57-8920, FAX: 81-743-56-5113, www.qualicaps.co.jp/en

Global Network
Qualicaps operates in Japan, Romania, USA, Spain, and Canada, providing capsules, equipment, and technology worldwide.
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Catalog excerpts

F-Labo Fully-Automatic Capsule Filling Machine-1

Mitsubishi Chemical Holdings Group Full-Automatic Capsule Filling Machine

 Open the catalog to page 1
F-Labo Fully-Automatic Capsule Filling Machine-2

Full-Automatic Capsule Filling Machine Qualicaps Co. provides domestic and foreign users with high quality hard gelatin capsules, PEG capsules, and HPMC capsules. Our high-speed fully-automatic capsule filling machine developed by Qualicaps has attained high reputation domestically and internationally, so we developed F-series for laboratory for study of drug formulation and manufacturing investigational new drugs. This filling machine enables filling of drugs of every dosage form and multilayer filling. It can fill all the samples for studying drug formulation such as powder, 3-layer granule,...

 Open the catalog to page 2
F-Labo Fully-Automatic Capsule Filling Machine-3

Features Rectification and Transportation of Capsule This filler is patented in 10 countries worldwide, and is adopted for all the equipment we developed and attains high reputation. The filler consists of a Rectifier with excellent accuracy of division, cap bushing, and body bushing, and it can be disassembled/assembled easily and precisely with the positioning pin. Separation of capsules Each capsule body is seated in the body disc by a vacuum shoe equipped with an O-ring. This O-ring serves as a shock-absorber preventing cracking of the capsule shoulders as it is placed in the bottom of capsule...

 Open the catalog to page 3
F-Labo Fully-Automatic Capsule Filling Machine-4

Powder filling (layer 1 filling section) This filler adopts the die-compress method, a general filling method, which enables filling capsules with minute quantities of drugs. The pressure shaped slag powder on the weight control disk is filled in capsule bodies after pushing up the shaped slag powder from beneath, scraping excessive powder away, and controlling the weight. Granule filling The filler adopts the 2-layer filling unit as an individually controllable mechanism by incorporating a volume-controllable square between the upper and lower shutters. It enables multi-layer filling of granule...

 Open the catalog to page 4
F-Labo Fully-Automatic Capsule Filling Machine-5

Replacement of filling unit ( layer 1 filling section ) The filling unit on two rails can be removed easily by loosening the fixing bolts and pulling the unit out. Changing of the size or overhaul cleaning can be performed more easily by moving the filling unit to a distant position. Joining The filler pushes up a capsule body with the joining pusher and houses it in the joining block, and then pushes up the body and the block synchronously to connect a cap to the body. Each cavity dimension is determined based on the know-how we have accumulated as a hard capsule manufacturer for past many years...

 Open the catalog to page 5
F-Labo Fully-Automatic Capsule Filling Machine-6

Romania Japan GLOBAL NETWORK Qualicaps Co., Ltd. 321-5 Ikezawacho,Yamatokoriyama Nara, 639-1032 Japan Phone: 81-743-57-8920 FAX : 81-743-56-5113 www.qualicaps.co.jp/en

 Open the catalog to page 6
*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.