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Endocrine Array

Product catalog summary

Overview: The Randox Endocrine Array is designed for the simultaneous determination of multiple hormones in a single sample, specifically targeting cortisol (CORT), dehydroepiandrosterone-sulphate (DHEAS), 17αHydroxyprogesterone (17αOHP), and leptin (LEPT). These hormones are crucial for human homeostasis and are associated with various health conditions.

Hormone Functions and Associated Conditions:

Cortisol (CORT): Involved in adrenal gland function, metabolism, and immune system regulation. Associated with stress, hypoglycemia, nutritional deprivation, adrenal/pituitary tumors, Cushing’s syndrome, Addison’s disease, and congenital adrenal hyperplasia (CAH).
Dehydroepiandrosterone-sulphate (DHEAS): Plays a role in adrenal gland function, immune response, and stress response. Linked to adrenal hirsutism, virilism, adrenal tumors, alopecia, and CAH.
17α Hydroxyprogesterone (17αOHP): Important for adrenal gland function and fertility disorders. Associated with CAH, hirsutism, and menstrual disturbances.
Leptin (LEPT): Maintains body weight and energy, involved in anorexia nervosa, hematopoiesis, adrenal cortex function, bone development, and immunoregulation.

Technical Specifications:

Utilizes chemiluminescent immunoassays suitable for human serum or plasma samples.
Requires a small sample volume of 25µl.
Offers excellent analytical performance with ready-to-use biochips.
Provides multi-analyte controls and calibrators.
Available in fully and semi-automated analyzers, catering to both large and medium-sized laboratories.

Performance and Precision:

Assay range and sensitivity for each hormone are specified, with typical intra-assay precision <12% and inter-assay precision ≤15%.

Product Information:

Endocrine Array (Evidence) - Cat. No. EV3711
Endocrine Array (Evidence Investigator) - Cat. No. EV3714
Endocrine Array Calibrators - Cat. No. EV3712
Endocrine Array Controls - Cat. No. EV3713

Additional Information: The Endocrine Array is intended for research purposes only and is not for diagnostic use in the USA. Randox Laboratories provides a wide range of complementary arrays, including Cytokine, Fertility Hormone, Metabolic Syndrome, and Thyroid Arrays.

Catalog excerpts

Endocrine Array Simultaneous determination of multiple hormones in a single sample

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Endocrine Array For hormone profiling with a single sample The Randox Endocrine Array has been developed to expand the biochip portfolio to include four major hormones important in human homeostasis. Cor tisol, dehydroepiandrosterone-sulphate (DHEAS) and 17α hydroxyprogesterone (17αOHP) are produced in the adrenal glands, the cor tisol/DHEAS ratio regulates multiple body functions and has been found to be a better predictor of health outcomes than the level of either hormone alone. 1 A positive association between cor tisol/DHEAS ratio and metabolic syndrome has been repor ted. 2 17αOHP is the...

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Performance outline on Evidence Investigator Analyte CORT DHEAs ng/ml µg/ml ng/ml Typical intra-assay precision: (n=20) <12% Typical inter-assay precision: (n=20) ≤15% 09/134,189/382 *The assay range may var y with batch of calibrators Biochip Systems emi-automated S 702 tests in 70 minutes edium size laboratories M edium throughput M ide test menu W Fully automated 1,980 tests per hour Large laboratories High throughput Wide test menu Complementary arrays available from Randox Product Endocrine Array (Evidence) Endocrine Array (Evidence Investigator) Endocrine Array Calibrators Endocrine Array...

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International Headquarters Randox Laboratories Limited, 55 Diamond Road, Crumlin, County Antrim, United Kingdom, BT29 4QY T +44 (0) 28 9442 2413 Australia Randox (Australia) Pty Ltd. Tel: +61 (0) 2 9615 4640 Brazil Randox Brasil Ltda. Tel: +55 11 5181-2024 China Randox Laboratories Ltd. Tel: +86 021 6288 6240 Czech Republic Randox Laboratories S.R.O. Tel: +420 2 1115 1661 Germany Randox Laboratories GmbH Tel: +49 (0) 2151/93 706-11 Hong Kong Randox Laboratories Hong Kong Limited Tel: +852 3595 0515 Italy Randox Laboratories Ltd. Tel: +39 06 9896 8954 India Randox Laboratories India Pvt Ltd. Tel:...

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