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LT169 Cardiac Array

LT169 Cardiac Array

LT169 Cardiac Array

Product catalog summary
Overview: The Cardiac Array is designed for early diagnosis of myocardial infarction (MI) and monitoring acute coronary syndrome (ACS). It detects up to four cardiac markers from a single patient sample, providing accurate quantitative results suitable for clinical and research settings.
Key Features:
  • Comprehensive assays for cardiovascular research.
  • Applicable in near-patient, central laboratory, and research settings.
  • 98% rule-out for MI within 3-6 hours post-pain onset.
  • Improved risk stratification for suspected ACS patients.
Compliance: The Cardiac Array meets ACC/ESC guidelines with assays for Troponin, CK-MB, and H-FABP achieving <10% CV at the 99th percentile of the normal range.
Cardiac Markers:
  • H-FABP: Early marker, detectable 30 minutes post-event, peaks at 6-8 hours, and normalizes within 20-24 hours. Highly sensitive.
  • Myoglobin: Early marker, rises 2-4 hours post-event, peaks at 6-12 hours.
  • Troponin I: Late marker, rises 4-6 hours post-event, remains elevated for 10-14 days. Highly specific but less sensitive early on.
  • CK-MB: Late marker, rises 4-6 hours post-event, remains elevated for 3-4 days. Highly specific but less sensitive early on.
Clinical Insights:
  • H-FABP, when measured with Troponin, aids early MI diagnosis.
  • H-FABP is more sensitive than Troponin within 4 hours of symptom onset.
  • Combining H-FABP and Troponin optimizes diagnostic performance.
  • H-FABP can identify high-risk MI patients and predict mortality post-ACS.
Performance Data: The Cardiac Array on the Evidence Investigator provides specific assay ranges and sensitivities for Troponin I, Myoglobin, CK-MB, and H-FABP.
Biochip Analyzers:
  • Evidence Evolution: Fully automated, suitable for high throughput, up to 2940 tests/hour.
  • Evidence: Fully automated, suitable for high throughput, >1500 tests/hour.
  • Evidence Investigator: Semi-automated, suitable for low to medium throughput, consolidates immunoassay and molecular testing.
Ordering Details: Various Cardiac Array models are available, including EV3692, EV3688, and EV3689, each compatible with different analyzers.
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Catalog excerpts

LT169 Cardiac Array-1

Cardiac Array For earlier diagnosis of Ml and monitoring of acute coronary syndrome

 Open the catalog to page 1
LT169 Cardiac Array-2

Simultaneous detection of up to four cardiac markers The Cardiac Array simultaneously detects up to four cardiac markers from a single patient sample, providing highly accurate quantitative results. Suitable for use within both a clinical and research setting, the Cardiac Array has a wide range of applications. • Comprehensive range of both routine and novel assays provides an excellent tool for research into cardiovascular disease • Near patient, central laboratory and research analysers available – suitable for all sizes of laboratory • 98% rule out for MI within 3-6 hours post pain onset –...

 Open the catalog to page 2
LT169 Cardiac Array-3

“The measurement of H-FABP, along with cTnI has shown to offer improved sensitivity over cTnI alone and provides a valuable accurate rule out test for MI within 3-6 hours.” “Measuring H-FABP in addition to Troponin at the time of admission with acute ischemic chest pain patients will assist in the early diagnosis of MI” 1 Peak Level “For patients presenting within 4h of symptom onset, the sensitivity of H-FABP is significantly higher than Troponin” 1 “To decrease the risk of falsely excluding ongoing AMI patients, the use of H-FABP and Troponin provides optimum diagnostic performance” 2 Time...

 Open the catalog to page 3
LT169 Cardiac Array-4

Biochip analysers Evidence Investigator • Semi-automated bench top system • Suitable for low to medium throughput laboratories • Consolidate immunoassay and molecular testing onto one platform Evidence • Fully automated system • Suitable for high throughput laboratories • Throughput of >1500 tests per hour Performance data Cardiac Array on Evidence Investigator Evidence Evolution • Fully automated system • Suitable for high throughput laboratories • Throughput of up to 2940 tests per hour Ordering Details Assay Range Cardiac Array Evidence Investigator Cardiac Array Cardiac Array Randox Laboratories...

 Open the catalog to page 4

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