Respiratory Multiplex Array II Rapid, simultaneous detection of 21 bacterial and viral pathogens of the upper and lower respiratory tract

RESPIRATORY MULTIPLEX ARRAY II Rapid, simultaneous detection of 21 bacterial and viral pathogens within the upper and lower respiratory tracts INTRODUCTION Respiratory tract infections (RTI) are caused by many viral and bacterial pathogens and are the second most common cause of morbidity and mortality worldwide.1 Acute respiratory disease (ARD) accounts for more than 4 million deaths annually and are the leading cause of death in developing countries.2 Viral respiratory infections can occur in epidemics and can spread rapidly within communities across the globe. Every year, influenza causes...

The Respiratory Multiplex Array is the most comprehensive diagnostic test for infections of both the upper and lower respiratory tracts, simultaneously detecting 21 bacterial and viral pathogens in nucleic acid extracted from a single sputum, lavage or nasopharyngeal sample. The assay is based on a combination of multiplex PCR and biochip array hybridisation. Innovative PCR priming technology permits high discrimination between multiple targets. A unique primer set is designed for each target which will hybridise to a complementary oligo-nucleotide probe spotted on a biochip discrete test region...

BENEFITS OF THE RANDOX RESPIRATORY MULTIPLEX ARRAY II PRODUCT FEATURES • Rapid turnaround time of ~6 hours from extracted genomic nucleic acid to result • ompatible with various sample matrices including sputum, lavage and nasopharyngeal samples C BENEFITS TO THE LABORATORY • imultaneously identifying the most prevalent pathogens, both viral and bacterial, will provide a S rapid and more cost-effective diagnostic tool than current tests, which detect single pathogens • One step RT-PCR • Inclusion of anti-contaminant enzyme as additional control measure • Optimised wash steps to minimise hands-on-time...

Mass gatherings, such as the Hajj increase the likelihood of the spread of infectious diseases. The Kingdom of Saudi Arabia annually hosts over 2 million Muslim pilgrims from around 184 countries during the Hajj pilgrimage, making it one of the largest and most culturally and geographically diverse mass gatherings in the world. Respiratory tract infections (RTIs) are the most common infection transmitted between pilgrims during Hajj, and most pilgrims develop RTIs during their few weeks stay in Makkah and Madinah. The Randox Respiratory Multiplex Array was used to screen for the presence of bacterial...

Evidence Investigator Rapid, accurate and comprehensive molecular testing The Evidence Investigator is a compact, semi-automated bench top platform consolidating molecular diagnostics and immunoassay on a single platform with protein and DNA biochips. Utilising revolutionary Biochip Array Technology (BAT), the Evidence Investigator allows simultaneous detection of multiple analytes from a single sample for efficient and costeffective testing. The Evidence Investigator molecular package includes the following: • 1 x Evidence Investigator analyser platform • PC biochip software • Barcode scanner...

Respiratory Multiplex Array 1. umla, A. et al. Emerging respiratory tract infections 4 Rapid point of care diagnostic tests Z for viral and bacterial respiratory tract infections – needs, advances, and future prospects. Lancet Infect Dis 2014. Available online: http://www.thelancet.com/pdfs/journals/laninf/PIIS1473-3099(14)70827-8.pdf. Last accessed January 2016. 2. orum of International Respiratory Societies. Respiratory Diseases in the World. F Realities of Today – Opportunities for Tomorrow. Available online: http://www.theunion.org/what-wedo/publications/technica;/english/FIRS_report_for_web.pdf....

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