Clinical Findings ORA for detection of corneal pathologies Compared to Pachymetry-matched controls, Corneal hysteresis was reduced in Keratoconus eyes (7.0±1.4 mm Hg vs. 8.8±1.2 mm Hg for controls, p=0.04) and Fuchs’ Corneal Dystrophy eyes (8.2±2.8 mm Hg vs. 12.1±1.7 mm Hg for controls, p=0.05). Similarly, mean CRF was lower in Keratoconus and Fuchs’ than in control eyes. This demonstrates that metrics of corneal rigidity may not correlate with central corneal thickness, and that corneal biomechanics reflect more than central corneal pachymetry alone. IOP and Corneal Biomechanical Metrics in Eyes With Keratoconus and Fuchs’ Dystrophy Compared to Pachymetry-Matched Controls. J.P. Sanderson, M.A. Qazi, C.J. Roberts, J.S. Pepose. Our data demonstrate that corneas with Fuchs’ Dystrophy have lower hysteresis measurements than do normal corneas. Patients who have undergone penetrating keratoplasty have hysteresis measurements similar to those of Fuchs’ patients, suggesting an alteration in corneal biomechanics even when the corneal graft is clear. Change in Axial Length Following Surgical Decompression. A Surrogate for the Material Properties of the Eye Wall. S.A. Tanimoto*†, L.A.S. Mello, Jr.,* J.D. Brandt† *Department of Ophthalmology, Escola Paulista de Medicina, São Paulo, Brazil †Department of Ophthalmology & Vision Science, University of California, Davis Ocular Response Analyzer www.ocularresponseanalyzer.com Reichert, Inc. 3362 Walden Avenue, Depew, NY 14043 Toll-free: 888-849-8955 Tel: (716) 686-4500 Fax: (716) 686-4545 www.reichertoi.com I I Understand the Cornea. Understand the Pressure.

Clinical Findings ORA for detection of corneal pathologies Compared to Pachymetry-matched controls, Corneal hysteresis was reduced in Keratoconus eyes (7.0±1.4 mm Hg vs. 8.8±1.2 mm Hg for controls, p=0.04) and Fuchs’ Corneal Dystrophy eyes (8.2±2.8 mm Hg vs. 12.1±1.7 mm Hg for controls, p=0.05). Similarly, mean CRF was lower in Keratoconus and Fuchs’ than in control eyes. This demonstrates that metrics of corneal rigidity may not correlate with central corneal thickness, and that corneal biomechanics reflect more than central corneal pachymetry alone. IOP and Corneal Biomechanical Metrics in...

In the multiple regression model incorporating CRF, CCT, and the other ocular variables, only CRF was significantly associated with GAT IOP values. Also, a positive correlation was observed between CRF and CCT and between CRF and corneal curvature. These findings seem to indicate that CRF is not solely a measure of corneal material properties, but rather is an index that aggregates the effects of CCT, tissue material properties, and corneal curvature. Felipe A. Medeiros, MD and Robert N. Weinreb, MD. Evaluation of the Influence of Corneal Biomechanical Properties on Intraocular Pressure Measurements...

Clinical Findings ORA for detection of corneal pathologies Compared to Pachymetry-matched controls, Corneal hysteresis was reduced in Keratoconus eyes (7.0±1.4 mm Hg vs. 8.8±1.2 mm Hg for controls, p=0.04) and Fuchs’ Corneal Dystrophy eyes (8.2±2.8 mm Hg vs. 12.1±1.7 mm Hg for controls, p=0.05). Similarly, mean CRF was lower in Keratoconus and Fuchs’ than in control eyes. This demonstrates that metrics of corneal rigidity may not correlate with central corneal thickness, and that corneal biomechanics reflect more than central corneal pachymetry alone. IOP and Corneal Biomechanical Metrics in...