Data Sheet Configure a resource-enabling TFF System with delivery in weeks KrosFlo® KTF Systems uniquely combine simplicity and configurability. Support for multiple scales, unit operations and applications maximize resource utilization. From design with an on-line configurator to running a concentration and diafiltration unit operation, expert engineering delivers precision performance, a positive user experience and accelerates timelines. Experience the ease and simplicity of designing on-line • Input requirements using pull down menus. • Download on-line engineering drawings within a day. • Receive as fast as 6 weeks ready-to-use Filter Format* Please choose -- Please choose -- - - Please choose -- - Please choose -- © Repligen Corporation. All rights reserved. All trademarks are the property of their respective owners. REPLIGEN INSPIRING ADVANCES IN BIOPROCESSING

Data Sheet Elevate resource utilization with popular configurations Design your system for flexibility across multiple parameters, such as volume, application, and filter type. Multiple pumps of different sizes augment volume capability. Multiple pump types at different positions expand application and filter type support. Volume flexibility Line 2 for small-scale 2 auxiliary pumps 2 magnetic levitating recirculating pumps • Configure for a wide range of batch sizes • Fully compatible with ProConnex® TFF Flow Paths • Line 1 supports up to 2500 L (KrosFlo® Max X06 Filter) • Line 2 supports up...

Data Sheet • Configure iFIX 6.0 Software to your process requirements • Generate batch reports using Dream Report® Configure ProConnex® Flow Paths for optimal process yield and safety • Configure a complete ProConnex® Flow Path from over 250 components: fittings, reservoirs, pressure transducers, aseptic connectors and more • Gamma-irradiated and packed conveniently in a ready-to-operate format • Ensure process, scale and application fit through engineering design • Generate 3D engineering drawings using on-line configurator © Repligen Corporation. All rights reserved. All trademarks are the...

1. Spectrum® Hollow Fiber Filter 2. Automatic back pressure control valve 4. Magnetic levitating pump 5. Retentate flow meter 6. Single-use pressure sensor 8. 304 Stainless steel frame 9. Permeate flow meter KrosFlo® KTF System dimensions Data Sheet * Specification dependent on your system configuration. © Repligen Corporation. All rights reserved. All trademarks are the property of their respective owners. REPLIGEN INSPIRING ADVANCES IN BIOPROCESSING

Data Sheet Service and support Available services include: technical consultation, system installation, training (on-site and virtual), IOQ qualification, preventive maintenance, warranty (Extended Factory) agreements, and service agreements. Support extends to implementation in a regulatory environment including executed Factory Acceptance Testing (FAT) documents and Site Acceptance Testing (SAT) protocols for on-site execution. © Repligen Corporation. All rights reserved. All trademarks are the property of their respective owners. REPLIGEN INSPIRING ADVANCES IN BIOPROCESSING

Data Sheet Manufacturing centers of excellence provide high quality and high-capacity KrosFlo® production facilities. Geographic redundancy, ISO Certification and dedicated Factory Acceptance Testing (FAT) execution zones ensure a compliant documentation system with a robust supply chain. Optional customer participation during FAT provides additional assurance. • Multiple geographic sites • On-site functions include: Document Control, Development, Engineering, Manufacturing, Purchasing, Quality Control and Assurance • High-capacity manufacturing • Single-site manufacturing: KrosFlo® TFF System...