FlowVPE Real-time Concentration Analytics During Purification Process The FlowVPE System unleashes the power of Slope Spectroscopy® with its unique patented variable pathlength technology on the online process monitoring and PAT fields. The FlowVPE has revealed process insights and enabled applications and innovations that help accelerate development, reduce risk, and increase process efficiency. The FlowVPE is adaptable to a wide range of sample types and concentrations. It can support lab scale flow lines of 3 mm (standard luer fitting) and pilot scale flow lines of 10 mm (1/2” Tri-clamp connection). Measure titer in real-time Real-time loading mass and elution mass Resin efficiency Modeling and impurity measurement Single pass or recirculating Accurately hit final target to 250 mg/ml Process control for SPTFF Real-time DAR and drug depletion curves for ADC’s • Removes sampling • Reduces process risk • Save time and materials