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Next generation software for KrosFlo® TFF Systems

Next generation software for KrosFlo® TFF Systems

Product catalog summary
Overview: The KF Comm 2 Software is designed for optimized Tangential Flow Filtration (TFF) using KrosFlo® TFF Systems. It features a menu-driven interface compatible with Windows OS and major web browsers, and is specifically designed for KrosFlo® KR2i and KrosFlo® KMPi TFF Systems.
Validation and Compliance: The software may be validated for Good Manufacturing Practice (GMP) processes and includes a 21 CFR Part 11 option, featuring a login module with electronic signature for tracking experiments.
Intuitive Workflow: The software supports 13 modes of operation, allowing real-time tracking from setup to analysis. These modes include:
  • Manual Mode (M): Manual operation of pumps and auxiliary components.
  • Continuous Mode (CONT): Manual operation with operator interface steps for concentration and diafiltration.
  • Concentration Mode (C): Automated concentration and flushing of the hollow fiber filter.
  • Concentration/Diafiltration (C/D): Sequential concentration and diafiltration of the process solution.
  • Concentration/Diafiltration/Concentration (C/D/C): Diafiltration with one buffer followed by a second concentration.
  • Concentration/Diafiltration/Diafiltration/Concentration (C/D/D/C): Diafiltration with two buffers followed by concentration.
  • Constant Feed Concentration (CFC): Concentration while maintaining constant feed weight.
  • Constant Feed Concentration/Diafiltration/Concentration (CF/D/C): Concentration with constant feed weight, buffer washing during diafiltration, followed by further concentration.
  • Vacuum Mode (V): Use of Constant Feed and/or Diafiltration Mode without auxiliary pumps, utilizing vacuum.
  • Flushing Mode (F): Flushing operation.
  • Normalized Water Permeability Mode (NWP): Determines filter cleanliness and water flux of new modules.
  • Cleaning Mode (C): Cleaning operation.
  • Flux Excursion Mode (FE): Measures flux rate.
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Catalog excerpts

Next generation software for KrosFlo® TFF Systems -1

Data Sheet KF Comm 2 Software features a menu-driven interface for performing optimized Tangential Flow Filtration (TFF) using KrosFlo® TFF Systems. It can be installed on most computers using the Windows Operating System and is compatible with Chrome, Mozilla, Firefox, or Microsoft Internet Explorer browsers. OPTIMIZED FOR KROSFLO® TFF SYSTEMS Designed for use with KrosFlo® KR2i and KrosFlo® KMPi TFF Systems Login module with electronic signature for tracking experiments Real-time tracking from set-up to analysis © Repligen Corporation. All rights reserved. All trademarks are the property of their respective owners. REPLIGEN INSPIRING ADVANCES IN BIOPROCESSING

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