PATsmart™ MAVEN® System Brochure
PATsmart™ MAVEN® System Brochure
- Real-Time Monitoring: Capable of acquiring data every 2 minutes, allowing for immediate detection and response to process changes.
- Advanced Process Control: Offers up to 720 data points per day to develop control strategies and identify improvement opportunities.
- Risk Mitigation: Utilizes a sample-free analysis method to reduce contamination risks.
- Precise Control: Maintains optimal glucose levels with biosensor-based measurement technology.
- Seamless Integration: Compatible with most upstream systems in process development and GMP manufacturing.
- Intuitive Automation: Features an integrated PID controller for direct pump control and connectivity with existing systems.
- Sensor Type: Enzyme-based electrochemical biosensor.
- Glucose Measurement Range: 0.01 to 40 g/L.
- Lactate Measurement Range: 0.05 to 10 g/L.
- Biosensor Service Life: 5,000 measurements or 30 days.
- Biologics: Enhances process yield and product quality by directing cellular metabolism.
- Cell & Gene Therapy: Improves CAR-T cell efficacy and MSC proliferation with glucose control.
- Viral Vector Production: Increases viral titer and capsid quality through dynamic substrate feeding control.
- Fermentation: Optimizes E.coli and yeast fermentation for recombinant protein production.
- Industrial Bio: Controls substrate feeding for meat cultivation processes.
- Enables dynamic feeding strategies to optimize cellular metabolism.
- Improves cell growth, viable cell density, and product yield.
- Enhances glycosylation profiles and reduces unwanted glycation.
Catalog excerpts
On-Line Bioprocess Analyzer On-line monitoring and real-time control of glucose and lactate
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Repligen Enabling Advanced Bioprocessing Meet MAVEN Optimized, automated glucose and lactate control Monitoring and control of glucose and lactate concentrations during cell culture and fermentation are critical to achieve optimal process efficiency and productivity for effortless realization of Process Analytical Technology (PAT) strategies. PATsmart™ MAVEN® provides invaluable real-time insights into cellular metabolism, enabling media optimization and smarter feeding and control strategies. Real-time data acquisition Detect and react to process changes in real time with on-line monitoring...
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Repligen Enabling Advanced Bioprocessing Designed with features to make your day Know exactly what’s happening in your bioreactor, maintain control of your process, and keep your cells happy Unlike in manual or automated sampling, measurements are performed without any loss of bioreactor volume and without increased risk of process contamination. Glucose and lactate molecules from the medium diffuse through the semi-permeable membrane into the transport buffer solution circulated between the probe and the measuring cell. Highly precise and robust biosensors The biosensor’s enzymatic recognition...
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Repligen Enabling Advanced Bioprocessing MAVEN loves to collaborate Monitor glucose and lactate in your bioreactor in real time. Refine feeding strategies on the fly. MAVEN easily integrates with upstream process development or GMP manufacturing systems Direct cellular metabolism towards higher efficiency and improve process yield and product quality. Process Analytical Technology (PAT) Continuous Monitoring of Glucose and Lactate Process Optimization Process Scale-Up and Out Process Feed Control Metabolic in silico modeling Compatible with most Bioreactors and Fermenters Automation Included...
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Boost your bioprocess today! © 2026 Repligen Corporation. All rights reserved. The trademarks mentioned herein are the property of Repligen Corporation and/or its affiliate(s) or their respective owners. MAVEN is subject to export controls including those of the Export Administration Regulations of the U.S. Department of Commerce, which may restrict or require licenses for the export of product from the United States and their re-export to and from other countries. | DOC0423 eRev. 2.0 26 Jan 2026 Repligen Corporation | www.repligen.com | [email protected]
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