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PATsmart™ REBEL® XT System Brochure

PATsmart™ REBEL® XT System Brochure

PATsmart™ REBEL® XT System Brochure

Product catalog summary
Introduction to REBEL XT
The PATsmart™ REBEL® XT is a cutting-edge cell culture media analyzer designed for rapid and efficient amino acid analysis. It leverages capillary electrophoresis and high-pressure mass spectrometry technologies to provide real-time insights into media composition, aiding in process development from cell line development to media quality control.

Importance of Cell Culture Media Analysis
Understanding and monitoring cell culture media is crucial in upstream bioprocessing. Real-time analysis of key components like amino acids helps in clone selection, feed strategy optimization, and improving product quality, ultimately leading to faster and more cost-effective product development.

REBEL XT Features and Benefits
  • Easy Operation: Minimal sample preparation is required, involving simple steps like pulling a sample, spinning, diluting, and loading.
  • Rapid Results: Provides a fully processed report for 22 analytes in just 15 minutes.
  • Data Integration: Facilitates easy data alignment with third-party platforms.
  • Comprehensive Analysis: Screens for 22 analytes including alanine, arginine, glutamine, and more.

Applications and Use Cases
  • CHO Media Screening: Monitors analytes throughout bioreactor time courses and refines feeding strategies.
  • Cell & Gene Therapy: Reduces development times for individualized therapeutics.
  • Viral Vector Production: Optimizes media for HEK293 or insect cells to enhance viral vector titers.
  • Fermentation and Industrial Bio: Analyzes bacterial medium and growth media components at any scale.
  • Biologics: Enhances cell productivity and critical quality attributes of biotherapeutics and vaccines.

Conclusion
The REBEL XT system offers a compact yet powerful solution for real-time media analysis, providing high accuracy and reproducibility. It supports various bioprocessing applications, from media quality control to bioreactor optimization, enabling faster and more efficient bioprocess development.
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Catalog excerpts

PATsmart™ REBEL® XT System Brochure-1

Boost your bioprocess Cell culture media analysis in minutes, not weeks.

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PATsmart™ REBEL® XT System Brochure-2

Repligen Enabling Advanced Bioprocessing Analysis in four easy steps Cell Culture Media analysis matters In upstream bioprocessing, understanding and monitoring cell culture media from the development stage through manufacturing is critical. Ultimately, having greater insight offers more opportunities to create products faster, more cost effectively, and with greater therapeutic success. Real-time analysis of key media components, such as amino acids, is beneficial at all stages of process development, including cell line development, media quality control, and media development. This information...

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PATsmart™ REBEL® XT System Brochure-3

Repligen Enabling Advanced Bioprocessing A comprehensive panel to meet your needs Easy to operate Designed for simplicity Minimal sample preparation Pull a sample from your bioreactor, shake flask or well plate, then spin out your cells and dilute. No more waiting for results Get a fully processed at-line report for 22 analytes in 15 minutes. Data integration Easy data alignment and interpretation with third-party platforms. Screens for 22 analytes in every run, all in 15 minutes Analytes Glutamic Acid Aspartic Acid

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PATsmart™ REBEL® XT System Brochure-4

Repligen Enabling Advanced Bioprocessing Know what's in your media How will you use REBEL XT? With the REBEL XT System, you can measure key nutrients in both fresh and spent media, at-line in real time, to gain deeper insight into your process and obtain high titer faster. Nine commercial CHO media were measured using the REBEL System in a media screening evaluation (Figure 1). This comparison shows that the concentrations of several amino acids, such as serine and arganine, two potentially important amino acids for cell growth and protein production, vary widely among the media tested, while...

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PATsmart™ REBEL® XT System Brochure-5

Boost your bioprocess today! © 2026 Repligen Corporation. All rights reserved. The trademarks mentioned herein are the property of Repligen Corporation and/or its affiliate(s) or their respective owners. REBEL XT is subject to export controls including those of the Export Administration Regulations of the U.S. Department of Commerce, which may restrict or require licenses for the export of product from the United States and their re-export to and from other countries. | DOC0424 eRev. 2.0 30 Jan 2026 Repligen Corporation | www.repligen.com | [email protected]

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.
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