PATsmart™ SoloVPE® PLUS System Product Specifications Specification Sheet Part ID: SYS-SOLO-P-VP-CARY60-CMP SYS-SOLO-P-VP-CARY60-CMP-CN (China) SYS-SOLO-P-VP-CARY60-CMP-JP (Japan) Overview The PATsmart™ SoloVPE® PLUS System is an enhanced version of the SoloVPE System, offering faster performance and an extended concentration measurement range without the need for dilution. Building on our unique and patented Variable Pathlength Technology (VPT), the SoloVPE PLUS System elevates the user’s experience with time savings and ease of use while maintaining the high accuracy and precision valued by leading biologic manufacturing companies for rapid at-line concentration measurement. Unlike traditional UV-Vis methods that generate a single absorbance result, the Slope Spectroscopy® method characterizes samples using multiple absorbance data points acquired at different pathlengths. The absorbance vs. pathlength data are verified in real-time for linearity in compliance with the Beer-Lambert law. The slope of the line is directly proportional to the sample concentration and extinction coefficient, delivering results in under a minute without the need for dilution or background correction. The SoloVPE PLUS System measures wavelengths from 190 nm to 1100 nm and pathlengths from 0.002 mm to 15.000 mm, accommodating various sample types and concentrations with proven accuracy and repeatability across systems, operators, and sites. Invest in the SoloVPE PLUS System to future-proof your lab, expand your capabilities, and stay at the forefront of analytical technology. repligen.com © 2026 Repligen Corporation. All rights reserved. The trademarks mentioned herein are the property of Repligen Corporation and/or its affiliate(s) or their respective owners. | DOC0361 eRev. 4.0 21 J

Specification Sheet PATsmart™ SoloVPE® PLUS System Features | Benefits *Photometric performance characteristics are based upon the Cary 60 spectrophotometer specifications and are applicable to the Cary 60 independent of the SoloVPE PLUS instrument. f Repeatability performance requires a properly validated method and controlled homogeneous samples. tSamples that are not homogeneous, suspensions, improperly mixed, or not in solution could produce unexpected results. This should be assessed during method development.

Specification Sheet PATsmart™ SoloVPE® PLUS System Required Computer Hardware Hard drive: 250 GB (SSD preferred) Final application suitability of all materials and ratings are the sole responsibility of the user. Specified pressure and temperature ratings may be subject to limitations. Contact a Repligen analytical representative for more information. More information Repligen Corporation and/or its affiliates, to the extent allowed by law, disclaims, and in no event shall be liable for, any incidental or consequential damages in connection with user, instrument, or system performance in relation...