Data Sheet Chromatography Systems Chromatography systems manufactured by Artesyn®, a Repligen Company, integrate multiple proprietary hardware and flow path innovations to deliver significantly higher product yields and operational success. Systems seamlessly scale from 1/4" - 1" ID tubing. Connectivity supports all major column formats, including full compatibility with OPUS® Pre-packed Columns. • Deliver optimal process yield with expert engineering • Reduce hold-up volume with proprietary valve technology • Increase productivity and reduce deviations with positive software user experience • Scale from 1/4" - 1" for development and commercial applications • Connect seamlessly with OPUS® Pre-packed Columns • Facilitate operation and training efficiency with platform solutions © ART svn* Innovative design and engineering increase yield and mitigate deviations © Repligen Corporation. All rights reserved. All trademarks are the property of their respective owners. REPLIGEN INSPIRING ADVANCES IN BIOPROCESSING

Data Sheet Chromatography Systems Chromatography systems manufactured by Artesyn® a Repligen Company, integrate multiple proprietary hardware and flow path innovations to deliver significantly higher product yields and operational success. Systems seamlessly scale from 1/4" - 1" ID tubing. Connectivity supports all major column formats, including full compatibility with OPUS® Pre-packed Columns. 5. HMI, touch screen and glass keyboard 6. Non-product contact liquid level switch 7. Multi-sensor OPTEK® converter (UV, pH, conductivity) 1. Multi-valve block arrays 3. Non-product contact ultrasonic...

Chromatography Systems Data Sheet Deliver high recovery, operational simplicity and superior connector strength with engineered flow paths Chromatography flow paths integrate advanced fluid management technologies, including over-molded connections, pump heads, tubing, filters and sensors in a strong, nearly leak-free, closed © ART svn I A REPLIGEN COMPANY and single-use device. Flow paths easily attach to the system to simplify operation and increase process efficiency. © Repligen Corporation. All rights reserved. All trademarks are the property of their respective owners. REPLIGEN INSPIRING...

Chromatography Systems Data Sheet Reduce hold up volume with synergistic valve and flow path technology Injection molded manifold and advanced valve block 1 2 Components 1. Pneumatic actuators 2. Manifold closure points 3. Overmolded joints with sterile connectors 4. Molded single-use flow path Innovative valve blocks direct fluids through uniform ID, crevice-free flow paths, achieving extremely low turbulence. Multi TEE injection molded silicone inserts, combined with over-molded connections minimize footprint and enable optimum closure point placement which significantly reduces dead leg. Traditional...

Chromatography Systems Data Sheet Scale-up chromatography Platform standardized chromatography systems scale from 1/4" to 1" flow path ID to support flow rates from 1 - 3000 LPH and OPUS® 8-80R Pre-packed Chromatography Columns. Consistent engineering design across the platform facilitates scale-up development studies and technical transfer. • Scale from 1/4" - 1" while maintaining system architecture and control platform • Implement off the shelf systems for fast lead times System flow rate System specifications © Repligen Corporation. All rights reserved. All trademarks are the property of...