AVENIO Edge System Technical specifications

Product catalog summary

General Specifications
The AVENIO Edge System is a floor model configuration capable of processing 1–48 samples per run for library preparation and target enrichment, with a runtime of up to 31 hours. Setup time is approximately 15 minutes, and it includes a pre-run consumable inventory check. Quality control is conducted using a fluorescence-based quantification method, and the system supports 2D and 1D barcode scanning. It is labeled US-IVD and CE-IVD compliant.

Kits and Applications
The system uses pre-filled, barcoded, ready-to-use reagent kits optimized for three runs, designed for extracted DNA samples. The workflow is based on hybridization-based target enrichment.

Software and Connectivity
The system ensures traceability with compliance to 21 CFR part 11, featuring an audit trail and process monitoring. Data can be exported in CSV, XML, and PDF formats, with sample input in .csv format. It includes two external USB ports, one network port, and connectivity options through AVENIO Connect Workflow Manager or HL7 LIS connection.

Deck Capacity
The deck can accommodate 17 tip racks, 6 processing plates, 5 processing lids, 2 quantification plates, 2 tip parks, 4 panel tubes, 15 control mini racks, 10 troughs, 20 cooled reagent tubes, and 2 primer plates. It supports inputs from MagNA Pure 96 output plates or MagNA Pure 24 8-tube strips.

Power and Environmental Requirements
The system requires a maximum pressure of less than 1 MPa per foot, operates at ambient temperatures of 15 ºC–30 ºC, and humidity levels of 30–80%. Power requirements are 110–240 VAC, 50/60 Hz.

Hardware Specifications
The instrument footprint is 1664 mm x 787 mm x 2032 mm, with an operating space of 2664 mm x 1987 mm x 2100 mm. It weighs 560.9 kg. The work deck is optimized to minimize contamination risk, featuring a single 8-channel pipetting head and a cooling block operating between 2 ºC–8 ºC. The on-deck thermocycler has a temperature range of +4°C to +99°C, with specific heating and cooling rates and temperature accuracy.

Quantification Module
The system includes a high-performance multimode plate reader powered by a monochromator.

Catalog excerpts

AVENIO Edge System Technical specifications-1

AVENIO Edge System Technical specifications General Configuration Floor model 1–48 samples for library prep and target enrichment Up to 31 hrs (including 16 hrs hybridization time) Setup time Approximately 15 mins prior to run Inventory check Pre-run consumable list. Pre-run check for empty positions and incorrectly placed items Quality control on deck Fluorescence-based quantification method 2D imager scans for 2D and 1D barcodes Regulatory label US-IVD, CE-IVD Kits and applications Reagent design Pre-filled, barcoded, ready-to-use. Reagent kits are optimized for 3 runs. Sample type Hybridization-based target enrichment Software and connectivity Traceability 21 CFR part 11 (subsection B), audit trail, process monitoring, user guidance Data export CSV, XML and PDF run exports. Sample input in .csv format 2 external USB ports and 1 network port AVENIO Connect Workflow Manager or HL7 LIS connection, Roche remote service solution Deck capacity Consumables 17 tip racks of 96 tips each, supporting 3 tip types (50 / 200 / 1000 μL) 6 processing plates 5 processing lids 2 quantification plates 2 tip parks 4 panel tubes (to reconstitute custom panels) 15 control mini racks; each rack includes 4 individual 2.0 ml tubes 10 troughs 20 cooled reagent tubes, 0.5 or 2.0 mL 2 primer plates 1 MagNA Pure 96 output plate or 12 MagNA Pure 24 8-tube strips, low or high profile, or 1 processing plate

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AVENIO Edge System Technical specifications-2

AVENIO Edge System Technical specifications Hardware Instrument footprint (WxDxH) Operating space (WxDxH) Construction and service space (WxDxH) Contamination control Work deck layout optimized to minimize contamination risk, UV light, optimized pipetting parameters with each TDF Pipetting head Single 8-channel pipetting head Cooling block On-deck thermocycler Temperature range thermal block: +4°C to +99°C Temperature range heated lid: +30°C to +115°C Maximum average heating rate: 4.4°C /sec Maximum average cooling rate: 2.2°C /sec Temperature accuracy: ±0.3°C at 55°C Temperature uniformity:...

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AVENIO Edge System Technical specifications-3

Signature Page for MC--05897 v3.0 Aprobación normativa Jessica Betts Regulatory 11-Mar-2022 16:25:00 GMT+0000 Signature Page for MC--05897 v3.0

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