The AVENIO Millisect System Optimize tumor yield with precise tissue dissection

Tissue dissection reinvented Current tissue dissection methods can prove either too crude or too complex. The AVENIO Millisect System, employing a simple yet precise FFPE tissue dissection technology, breaks the mold – empowering you to extract the most clinically relevant information from challenging tumor samples. Clean samples, clear profiles Manual dissection can risk accidental contamination with adjancent normal tissue, and laser capture microdissection (LCM) can risk sample loss. The AVENIO Millisect System allows you to optimize tumor yield and improve sample recovery from difficult-to-dissect...

Consistent Annotation Magnification, digital alignment and annotation of up to 4 slides provide consistent and reproducible tissue dissection. Precise Dissection Fine recovery of AOIs as small as 250 pm in diameter are achieved by the AVENIO Millisect Milling Tip. Gentle Recovery Gentle capillary action draws and expels dissected tissue into a collection tube in a hands-free process. Digital Report A PDF report that tracks sample IDs, annotations, pre-and post-dissection images and notes, is automatically generated.

Optimize tumor yield Tumor heterogeneity or low cellularity can make it difficult to isolate clinically relevant cells without contamination from normal adjacent tissue. The AVENIO Millisect System helps you tackle complex tumor cases by improving sample recovery with precise dissection. Reduce contamination and improve tumor yield The AVENIO Millisect System allows users to capture complex tumors as small as 250 μm in diameter. This fine control enables users to increase the percentage of neoplastic cells captured in a sample relative to manual dissection.1 Serial sections from a heterogeneous...

Each cancer profile is unique, and developing a complete molecular portrait of a tumor can open doors to new treatment options. In comparison studies, targeted dissection of the AVENIO Millisect System has been shown to reduce false-negative results and uncover more actionable tumor information than manual dissection.1,2 Reduce false-negative results In tests in pancreatic tumor samples, the AVENIO Millisect System enabled detection of KRAS mutations missed with manual dissection.1 # AVENIO Millisect System # Manual A total of 32 matched pairs of FFPE samples from 18 pancreatic ad enocarcinoma...

Improve laboratory workflow The information contained in each tissue sample is complex, but the process of uncovering it should not be. Designed for routine clinical use, the AVENIO Millisect System can be readily adopted into existing workflows, minimizing demands on staff. Achieve workflow efficiency, consistency and traceability As opposed to cumbersome, uncontrolled manual dissection or complicated, timeconsuming LCM, the AVENIO Millisect System brings precision and simplicity to molecular pathology laboratories around the world. Its automated, digitally assisted workflow ensures sample acquisition...

“ ...digitally guided microdissection can enrich tumor content well beyond manual macrodissection...” – Early Evaluation Program customer, USA Catalog information Roche Cat. No. Pack Size AVENIO Millisect Instrument, Base AVENIO Millisect Instrument, Head AVENIO Millisect Milling Tips S AVENIO Millisect Milling Tips M AVENIO Millisect Milling Tips L AVENIO Millisect Fill Station VANTAGE BCR - Handheld - Honeywell* VANTAGE BCR Stand Rigid - Honeywell* VANTAGE BCR Stand Flexible - Honeywell* **Optional Barcode Scanner for purchase References: 1. Geiersbach K et al. Cancer Genet. 2016;209(1-2):42-49....

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