MagNA Pure 96 Brochure

MagNA Pure 96 Brochure
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MagNA Pure 96 Brochure

Product catalog summary
Overview: The MagNA Pure 96 System is an advanced instrument designed for high-throughput, automated nucleic acid purification. It can process up to 96 samples in less than an hour, enhancing laboratory efficiency by automating the isolation of DNA, RNA, and viral nucleic acids using magnetic glass particle technology.
Key Features:
  • Automated purification with pre-programmed protocols for various sample types.
  • High throughput capacity for 96 samples per run.
  • User-friendly software interface for easy operation and error detection.
  • Efficient data management with LIMS connectivity and audit trails.
  • Contamination prevention through UV lamps and CO-RE Tip technology.
Reagent Kits: The system utilizes prefilled, barcoded reagent kits for convenience and safety. Available kits include:
  • Small Volume Kit: For genomic DNA, bacterial DNA, and viral DNA/RNA from diverse samples.
  • Large Volume Kit: Similar applications with added capacity for cell-free nucleic acids.
  • Cellular RNA Large Volume Kit: Designed for total RNA extraction.
Performance and Scalability:
  • Proven performance with over 20 years of magnetic bead technology.
  • Consistent high-quality extracts with reliable yields.
  • Scalable to accommodate varying laboratory demands, from low to high throughput.
Technical Specifications:
  • Benchtop standalone instrument with a separate control unit.
  • Sample input volume ranges from 50 µL to 4 mL.
  • Elution volume between 50 to 200 µL.
  • Run time varies from 50 to 90 minutes depending on the protocol.
  • Regulatory compliance with IVD directive 98/79/EC.
Applications: The system supports a wide range of sample types, including whole blood, plasma, serum, tissues, and more, with over 30 protocols available. It is suitable for various genomic applications, including real-time PCR and next-generation sequencing.
Conclusion: The MagNA Pure 96 System provides a robust solution for laboratories needing efficient, high-throughput nucleic acid purification with minimal handling errors and contamination risks. Its scalability and automation capabilities make it a valuable asset for both routine and high-demand testing environments.
Product Overview: The document details components and consumables for the MagNA Pure 96 System, used for RNA and DNA isolation. Key products include the 96 Cellular RNA LV Kit, MagNA Pure 96 System Fluids, and various lysis buffers.
Key Components:
  • 96 Cellular RNA LV Kit: Capable of up to 288 isolations.
  • MagNA Pure 96 System Fluid (Internal and External): Includes two internal containers and one external container.
  • Lysis Buffers: Includes External Lysis Buffer, Bacterial Lysis Buffer, and DNA Tissue Lysis Buffer.
  • MagNA Pure cfNA Buffer Set: Supports up to 96 isolations.
Consumables:
  • MagNA Pure 96 Processing Cartridge: 36 units.
  • MagNA Pure 96 Output Plate: 60 units.
  • MagNA Pure Filter Tip 1000µl: 8 packs of 5.
  • MagNA Pure Sealing Foil: 100 units.
  • MagNA Pure 96 Internal Control Tube: 150 units (15 packs of 10).
Additional Information: For further details or updated protocols, contact your local Roche representative or visit the website magnapure96.com.
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Catalog excerpts

MagNA Pure 96 Brochure-1

MagNA Pure 96 System Start here. Go anywhere.

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MagNA Pure 96 Brochure-2

Start here. The MagNA Pure 96 System is a high-throughput instrument for automated nucleic acid purification. Typical run duration is less than one hour for 96 standard volume samples. Experience high throughput automation combined with high performance while increasing your laboratory productivity to meet your changing needs. • Isolate DNA, RNA, and viral nucleic acids from a wide range of starting materials. • Simplify your workflow with pre-programmed protocols tailored to different sample requirements. • Utilize proven magnetic glass particle technologies. • ely on eluates suitable for a...

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MagNA Pure 96 Brochure-3

MagNA Pure 96 Reagent Kits Prefilled, barcoded, and ready-to use MagNA Pure 96 Kits are prefilled and ready-to-use reagent trays that can be easily loaded into racks, ensuring user ease and safety. These kits, as well as the consumables, are barcoded and read by the MagNA Pure onboard scanner for inventory check, loading errors, and process documentation. * For life science research only. Not for use in diagnostic procedures. MagNA Pure 96 Software Intuitive user interface The intuitive graphical user interface provides all instructions to operate the system, such as sample loading to run start....

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MagNA Pure 96 Brochure-4

^ Over 20 years of successful magnetic bead technology ^ High quality extract with reproducible and consistent yields ^ GMP-manufactured and IVD registered ^ Dedicated, experienced support and service teams Simplified Workflow ^ Ready-to-use prefilled reagents ^ Minimal consumables ^ On-board barcode scanning for inventory ^ Streamlined kit offering that purify a variety of nucleic acids ^ Intuitive graphical interface Contamination Prevention ^ UV lamp ^ Drop catcher ^ CO-RE Tip technology with stable lock-and-key fit which eliminates the risk of cross-contamination

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MagNA Pure 96 Brochure-5

^ 96 samples in less than one hour ^ Parallel handling of all samples with 2 robotic arms ^ Set-up in less than 5 minutes Accelerated Results Data Management ^ Software with audit trail and user management ^ LIMS host connectivity Optimized Productivity ^ Broad range of supported samples ^ Pre-programmed protocols, including “Pathogen Universal” that extracts DNA and RNA from 10 common samples ^ Eluate used for a variety of downstream applications Minimized Handling Error ^ Fully automated workflow ^ Error detection with corrective action guidance ^ Deck and volume surveillance ^ Barcoding of...

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MagNA Pure 96 Brochure-6

Flexibility for optimized productivity Efficient Purification 2.0 10600 K/µl Experiment details Kit: MagNA Pure 96 DNA and Viral NA SV Kit Protocol: SV Blood protocol Sample: Whole blood with various white blood cell counts ( 3700, 5800, 10600 K/µL) DNA was measured with the UV-spectrophotometer. The alignment of the duplicate curves for the varying cell count indicates reproducibility and scalability of the MagNA Pure 96 Instrument. Flexibility along with convenience 40.00 β-globin βGlobin Crossing Point A variety of targets from a wide range of sample types can be extracted efficiently on the...

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MagNA Pure 96 Brochure-7

Increase efficiency in pathogen detection The Roche workflow makes pathogen detection reliable and consistent. The high throughput MagNA Pure 96 System dramatically speeds up extraction by allowing different sample types to be supported by the same kit and protocols which enables faster downstream analysis. Increase efficiency even further with multiplex qPCR and assay panels offered by TIB MolBiol which can be run the LightCycler® 480 instrument. Parasite Panel Experiment details Kit: MagNA Pure 96 DNA and Viral NA SV Kit Pretreatment: As described in IFU Protocol: Pathogen Universal Sample:...

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MagNA Pure 96 Brochure-8

High throughput and scalability Prevention of contamination Three runs (each with 48 positive spiked plasma samples and 48 negative samples arranged in a checkerboard pattern) were extracted on the MagNA Pure 96 System and then analyzed on the LightCycler® 480 System. No cross-contamination was found. Experiment details Kit: MagNA Pure 96 DNA and Viral NA LV Kit Protocol: Large Volume Protocol (500µL) Sample: EDTA Plasma Pathogen: Parvo B19 at 5 x 10^7 copies/mL (=10^6 above detection limit) Highly reproducible results qPCR results from MagNA Pure 96 extracted samples are highly reproducible...

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MagNA Pure 96 Brochure-9

Growing with your needs Scale with ease Go anywhere with scalability for your lab’s growth. The MagNA Pure 96 Instrument is significantly faster than two other competitor brands. When considering daily, monthly and yearly capacity needs, the MagNA Pure 96 Instrument provides increased ability to meet growth and testing fluctuations.1,2 Buccal Swab Roche Testing Capacity (In Samples) Whole Blood Roche Beyond extraction Experiment details Unlock more of the answers you need with the new 4 mL volume protocol for circulating cell-free nucleic acids (cfNA) on the MagNA Pure 96 System by preferentially...

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MagNA Pure 96 Brochure-10

Start here. The MagNA Pure 96 System family ensures purity, reproducibility, and laboratory efficiency obtained only by automated bead-based extraction. Whether your lab extracts just a few samples or thousands in one day, the MagNA Pure family has a fully automated extraction to meet your scalable needs. From low throughput days • Simplified sample preparation for dramatic reduction of handling errors • Preloaded protocols for a broad range of sample types • re-filled and barcoded reagent kits P • Intuitive software and guidance MagNA Pure 24 System 1-24 Samples | Not available for sale To high...

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MagNA Pure 96 Brochure-12

Ordering informationMagNA Pure 96 Instrument, Kits, and Consumables Product Name For more information or general inquiries, or to obtain updated protocols, please contact your local Roche representative or visit magnapure96.com Published by Roche Molecular Systems, Inc 4300 Hacienda Drive Pleasanton, CA 94588 USA All MagNA Pure 96 Kits, Consumables, and Accessories are for in vitro diagnostic unless otherwise noted. * For life science research only Not for use in diagnostic procedures. t For general laboratory use. MAGNA PURE and LIGHTCYCLER are registered trademarks of Roche. All other product...

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